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Common Structural Pattern for Flecainide Binding in Atrial-Selective K(v)1.5 and Na(v)1.5 Channels: A Computational Approach

Atrial fibrillation (AF) is the most common cardiac arrhythmia. Its treatment includes antiarrhythmic drugs (AADs) to modulate the function of cardiac ion channels. However, AADs have been limited by proarrhythmic effects, non-cardiovascular toxicities as well as often modest antiarrhythmic efficacy...

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Detalles Bibliográficos
Autores principales:	Mazola, Yuliet, Márquez Montesinos, José C. E., Ramírez, David, Zúñiga, Leandro, Decher, Niels, Ravens, Ursula, Yarov-Yarovoy, Vladimir, González, Wendy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318806/ https://www.ncbi.nlm.nih.gov/pubmed/35890252 http://dx.doi.org/10.3390/pharmaceutics14071356

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