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Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania
Most cases of envenomation by common European vipers (Vipera berus) have not been reported to have neurotoxic manifestations. However, these manifestations have been demonstrated in some cases of envenomation by subspecies of V. berus, found in the Carpathian Basin region of south-eastern Europe. He...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318827/ https://www.ncbi.nlm.nih.gov/pubmed/35878238 http://dx.doi.org/10.3390/toxins14070500 |
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author | Nițescu, Gabriela Viorela Ulmeanu, Coriolan Emil Crăciun, Maria-Dorina Ciucă, Alina Maria Ulici, Alexandru Ghira, Ioan Lonati, Davide |
author_facet | Nițescu, Gabriela Viorela Ulmeanu, Coriolan Emil Crăciun, Maria-Dorina Ciucă, Alina Maria Ulici, Alexandru Ghira, Ioan Lonati, Davide |
author_sort | Nițescu, Gabriela Viorela |
collection | PubMed |
description | Most cases of envenomation by common European vipers (Vipera berus) have not been reported to have neurotoxic manifestations. However, these manifestations have been demonstrated in some cases of envenomation by subspecies of V. berus, found in the Carpathian Basin region of south-eastern Europe. Here, we report the case of a 5-year-old girl from the south of Romania who presented symptoms of neurotoxicity, as well as other systemic and local symptoms, after being bitten by an adder of the V. berus subspecies. Treatment consisted of monovalent antivenom, a corticosteroid, and prophylactic enoxaparin. Neurotoxic manifestations of envenomation as well as other local and systemic symptoms improved within 5 days of treatment. The presented case shows that venom from V. berus subspecies found in the Carpathian Basin can have neurotoxic effects. This case also confirmed the efficacy of monospecific antivenom treatment in bringing about rapid and complete remission, following envenomation. |
format | Online Article Text |
id | pubmed-9318827 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93188272022-07-27 Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania Nițescu, Gabriela Viorela Ulmeanu, Coriolan Emil Crăciun, Maria-Dorina Ciucă, Alina Maria Ulici, Alexandru Ghira, Ioan Lonati, Davide Toxins (Basel) Case Report Most cases of envenomation by common European vipers (Vipera berus) have not been reported to have neurotoxic manifestations. However, these manifestations have been demonstrated in some cases of envenomation by subspecies of V. berus, found in the Carpathian Basin region of south-eastern Europe. Here, we report the case of a 5-year-old girl from the south of Romania who presented symptoms of neurotoxicity, as well as other systemic and local symptoms, after being bitten by an adder of the V. berus subspecies. Treatment consisted of monovalent antivenom, a corticosteroid, and prophylactic enoxaparin. Neurotoxic manifestations of envenomation as well as other local and systemic symptoms improved within 5 days of treatment. The presented case shows that venom from V. berus subspecies found in the Carpathian Basin can have neurotoxic effects. This case also confirmed the efficacy of monospecific antivenom treatment in bringing about rapid and complete remission, following envenomation. MDPI 2022-07-18 /pmc/articles/PMC9318827/ /pubmed/35878238 http://dx.doi.org/10.3390/toxins14070500 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Nițescu, Gabriela Viorela Ulmeanu, Coriolan Emil Crăciun, Maria-Dorina Ciucă, Alina Maria Ulici, Alexandru Ghira, Ioan Lonati, Davide Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania |
title | Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania |
title_full | Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania |
title_fullStr | Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania |
title_full_unstemmed | Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania |
title_short | Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania |
title_sort | neurotoxicity and other clinical manifestations of a common european adder (vipera berus) bite in romania |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318827/ https://www.ncbi.nlm.nih.gov/pubmed/35878238 http://dx.doi.org/10.3390/toxins14070500 |
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