Cargando…

Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania

Most cases of envenomation by common European vipers (Vipera berus) have not been reported to have neurotoxic manifestations. However, these manifestations have been demonstrated in some cases of envenomation by subspecies of V. berus, found in the Carpathian Basin region of south-eastern Europe. He...

Descripción completa

Detalles Bibliográficos
Autores principales: Nițescu, Gabriela Viorela, Ulmeanu, Coriolan Emil, Crăciun, Maria-Dorina, Ciucă, Alina Maria, Ulici, Alexandru, Ghira, Ioan, Lonati, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318827/
https://www.ncbi.nlm.nih.gov/pubmed/35878238
http://dx.doi.org/10.3390/toxins14070500
_version_ 1784755393814069248
author Nițescu, Gabriela Viorela
Ulmeanu, Coriolan Emil
Crăciun, Maria-Dorina
Ciucă, Alina Maria
Ulici, Alexandru
Ghira, Ioan
Lonati, Davide
author_facet Nițescu, Gabriela Viorela
Ulmeanu, Coriolan Emil
Crăciun, Maria-Dorina
Ciucă, Alina Maria
Ulici, Alexandru
Ghira, Ioan
Lonati, Davide
author_sort Nițescu, Gabriela Viorela
collection PubMed
description Most cases of envenomation by common European vipers (Vipera berus) have not been reported to have neurotoxic manifestations. However, these manifestations have been demonstrated in some cases of envenomation by subspecies of V. berus, found in the Carpathian Basin region of south-eastern Europe. Here, we report the case of a 5-year-old girl from the south of Romania who presented symptoms of neurotoxicity, as well as other systemic and local symptoms, after being bitten by an adder of the V. berus subspecies. Treatment consisted of monovalent antivenom, a corticosteroid, and prophylactic enoxaparin. Neurotoxic manifestations of envenomation as well as other local and systemic symptoms improved within 5 days of treatment. The presented case shows that venom from V. berus subspecies found in the Carpathian Basin can have neurotoxic effects. This case also confirmed the efficacy of monospecific antivenom treatment in bringing about rapid and complete remission, following envenomation.
format Online
Article
Text
id pubmed-9318827
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-93188272022-07-27 Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania Nițescu, Gabriela Viorela Ulmeanu, Coriolan Emil Crăciun, Maria-Dorina Ciucă, Alina Maria Ulici, Alexandru Ghira, Ioan Lonati, Davide Toxins (Basel) Case Report Most cases of envenomation by common European vipers (Vipera berus) have not been reported to have neurotoxic manifestations. However, these manifestations have been demonstrated in some cases of envenomation by subspecies of V. berus, found in the Carpathian Basin region of south-eastern Europe. Here, we report the case of a 5-year-old girl from the south of Romania who presented symptoms of neurotoxicity, as well as other systemic and local symptoms, after being bitten by an adder of the V. berus subspecies. Treatment consisted of monovalent antivenom, a corticosteroid, and prophylactic enoxaparin. Neurotoxic manifestations of envenomation as well as other local and systemic symptoms improved within 5 days of treatment. The presented case shows that venom from V. berus subspecies found in the Carpathian Basin can have neurotoxic effects. This case also confirmed the efficacy of monospecific antivenom treatment in bringing about rapid and complete remission, following envenomation. MDPI 2022-07-18 /pmc/articles/PMC9318827/ /pubmed/35878238 http://dx.doi.org/10.3390/toxins14070500 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Nițescu, Gabriela Viorela
Ulmeanu, Coriolan Emil
Crăciun, Maria-Dorina
Ciucă, Alina Maria
Ulici, Alexandru
Ghira, Ioan
Lonati, Davide
Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania
title Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania
title_full Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania
title_fullStr Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania
title_full_unstemmed Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania
title_short Neurotoxicity and Other Clinical Manifestations of a Common European Adder (Vipera berus) Bite in Romania
title_sort neurotoxicity and other clinical manifestations of a common european adder (vipera berus) bite in romania
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318827/
https://www.ncbi.nlm.nih.gov/pubmed/35878238
http://dx.doi.org/10.3390/toxins14070500
work_keys_str_mv AT nitescugabrielaviorela neurotoxicityandotherclinicalmanifestationsofacommoneuropeanadderviperaberusbiteinromania
AT ulmeanucoriolanemil neurotoxicityandotherclinicalmanifestationsofacommoneuropeanadderviperaberusbiteinromania
AT craciunmariadorina neurotoxicityandotherclinicalmanifestationsofacommoneuropeanadderviperaberusbiteinromania
AT ciucaalinamaria neurotoxicityandotherclinicalmanifestationsofacommoneuropeanadderviperaberusbiteinromania
AT ulicialexandru neurotoxicityandotherclinicalmanifestationsofacommoneuropeanadderviperaberusbiteinromania
AT ghiraioan neurotoxicityandotherclinicalmanifestationsofacommoneuropeanadderviperaberusbiteinromania
AT lonatidavide neurotoxicityandotherclinicalmanifestationsofacommoneuropeanadderviperaberusbiteinromania