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Application of Parallel Reaction Monitoring to the Development and Validation of a Quantitative Assay for ST-246 in Human Plasma

In this work, we developed and validated a robust and sensitive method of liquid chromatography with high-resolution mass spectrometry in parallel reaction monitoring (PRM) mode for ST-246 (tecovirimat) quantification in human blood plasma. The method was compared with the multiple reaction monitori...

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Detalles Bibliográficos
Autores principales: Chernonosov, Alexander A., Oleinik, Galina A., Koval, Vladimir V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318837/
https://www.ncbi.nlm.nih.gov/pubmed/35887368
http://dx.doi.org/10.3390/ijms23148021