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Co-Delivery of 5-Fluorouracil and Paclitaxel in Mitochondria-Targeted KLA-Modified Liposomes to Improve Triple-Negative Breast Cancer Treatment

In this research, KLA-modified liposomes co-loaded with 5-fluorouracil and paclitaxel (KLA-5-FU/PTX Lps) were developed, and their antitumor activity against triple-negative breast cancer (TNBC) was evaluated. KLA-5-FU/PTX Lps were prepared using the thin-film dispersion method, and their in vitro a...

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Detalles Bibliográficos
Autores principales: Chen, Tianyu, Chen, Hui, Jiang, Yichun, Yan, Qi, Zheng, Shuling, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318860/
https://www.ncbi.nlm.nih.gov/pubmed/35890181
http://dx.doi.org/10.3390/ph15070881