Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors

We present a case demonstrating that older age does not exclude long-term survival with glioblastoma. This is a malignant neoplasm with a median life expectancy of 14 months in patients treated with radical intent. Survival is dependent on several independent and interacting prognostic factors of wh...

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Detalles Bibliográficos
Autores principales: McKinley, Aidan, Lammy, Simon, James, Allan, Stan, Alexandru, Barrett, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318890/
https://www.ncbi.nlm.nih.gov/pubmed/35903619
http://dx.doi.org/10.1093/omcr/omac074
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author McKinley, Aidan
Lammy, Simon
James, Allan
Stan, Alexandru
Barrett, Chris
author_facet McKinley, Aidan
Lammy, Simon
James, Allan
Stan, Alexandru
Barrett, Chris
author_sort McKinley, Aidan
collection PubMed
description We present a case demonstrating that older age does not exclude long-term survival with glioblastoma. This is a malignant neoplasm with a median life expectancy of 14 months in patients treated with radical intent. Survival is dependent on several independent and interacting prognostic factors of which advancing age is a negative factor. We present a septuagenarian with a 3.5-year survival following aggressive management. The potential to improve glioblastoma survival in an elderly population by examination of additional prognostic factors and identifying biomarkers warrants further research.
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spelling pubmed-93188902022-07-27 Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors McKinley, Aidan Lammy, Simon James, Allan Stan, Alexandru Barrett, Chris Oxf Med Case Reports Case Report We present a case demonstrating that older age does not exclude long-term survival with glioblastoma. This is a malignant neoplasm with a median life expectancy of 14 months in patients treated with radical intent. Survival is dependent on several independent and interacting prognostic factors of which advancing age is a negative factor. We present a septuagenarian with a 3.5-year survival following aggressive management. The potential to improve glioblastoma survival in an elderly population by examination of additional prognostic factors and identifying biomarkers warrants further research. Oxford University Press 2022-07-26 /pmc/articles/PMC9318890/ /pubmed/35903619 http://dx.doi.org/10.1093/omcr/omac074 Text en © The Author(s) 2022. Published by Oxford University Press. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
McKinley, Aidan
Lammy, Simon
James, Allan
Stan, Alexandru
Barrett, Chris
Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors
title Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors
title_full Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors
title_fullStr Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors
title_full_unstemmed Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors
title_short Emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors
title_sort emergency surgical decompression and long-term survival of glioblastoma presenting in coma in old age: case report and review of prognostic factors
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318890/
https://www.ncbi.nlm.nih.gov/pubmed/35903619
http://dx.doi.org/10.1093/omcr/omac074
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