Cargando…

Early Clinical Experience with Molnupiravir for Mild to Moderate Breakthrough COVID-19 among Fully Vaccinated Patients at Risk for Disease Progression

Information on the efficacy and safety of molnupiravir in daily clinical practice is very scarce. We aimed to describe the clinical characteristics and outcomes of fully vaccinated patients with mild to moderate breakthrough COVID-19 treated with molnupiravir between January 2022 and February 2022....

Descripción completa

Detalles Bibliográficos
Autores principales:	Vena, Antonio, Traman, Luca, Bavastro, Martina, Limongelli, Alessandro, Dentone, Chiara, Magnè, Federica, Giacobbe, Daniele Roberto, Mikulska, Malgorzata, Taramasso, Lucia, Di Biagio, Antonio, Bassetti, Matteo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318911/ https://www.ncbi.nlm.nih.gov/pubmed/35891305 http://dx.doi.org/10.3390/vaccines10071141

Ejemplares similares

Higher Mortality and Intensive Care Unit Admissions in COVID-19 Patients with Liver Enzyme Elevations
por: Taramasso, Lucia, et al.
Publicado: (2020)

Clinical presentation of secondary infectious complications in COVID-19 patients in intensive care unit treated with tocilizumab or standard of care
por: Taramasso, Lucia, et al.
Publicado: (2021)

Prevalence and Clinical Significance of Persistent Viral Shedding in Hospitalized Adult Patients with SARS-CoV-2 Infection: A Prospective Observational Study
por: Vena, Antonio, et al.
Publicado: (2021)

Extensive activation, tissue trafficking, turnover and functional impairment of NK cells in COVID-19 patients at disease onset associates with subsequent disease severity
por: Bozzano, Federica, et al.
Publicado: (2021)

Prevalence of Viral Hepatitis in Unselected, Consecutively Enrolled Patients Hospitalised for SARS-CoV-2
por: Dettori, Silvia, et al.
Publicado: (2022)

New antibiotics for Gram-negative pneumonia
por: Bassetti, Matteo, et al.
Publicado: (2022)

Healthcare Worker Study Cohort to Determine the Level and Durability of Cellular and Humoral Immune Responses after Two Doses of SARS-CoV-2 Vaccination
por: Dentone, Chiara, et al.
Publicado: (2022)

Case report: Sotrovimab, remdesivir and nirmatrelvir/ritonavir combination as salvage treatment option in two immunocompromised patients hospitalized for COVID-19
por: Baldi, Federico, et al.
Publicado: (2023)

Challenges in the diagnosis and treatment of candidemia due to multidrug-resistant Candida auris
por: Giacobbe, Daniele Roberto, et al.
Publicado: (2023)

Validation of an Automated System for the Extraction of a Wide Dataset for Clinical Studies Aimed at Improving the Early Diagnosis of Candidemia
por: Giacobbe, Daniele Roberto, et al.
Publicado: (2023)

Nirmatrelvir/Ritonavir and Molnupiravir in the Treatment of Mild/Moderate COVID-19: Results of a Real-Life Study
por: Gentile, Ivan, et al.
Publicado: (2022)

Bronchoalveolar lavage fluid characteristics and outcomes of invasively mechanically ventilated patients with COVID-19 pneumonia in Genoa, Italy
por: Dentone, Chiara, et al.
Publicado: (2021)

Reply to: “Antiviral Activity and Safety of Darunavir/Cobicistat for Treatment of COVID-19”
por: Nicolini, Laura Ambra, et al.
Publicado: (2020)

Spread of Carbapenem-Resistant Gram-Negatives and Candida auris during the COVID-19 Pandemic in Critically Ill Patients: One Step Back in Antimicrobial Stewardship?
por: Magnasco, Laura, et al.
Publicado: (2021)

Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy
por: Vena, Antonio, et al.
Publicado: (2020)

Duration of isolation and precautions in immunocompromised patients with COVID-19
por: Taramasso, L., et al.
Publicado: (2021)

External validation of unsupervised COVID-19 clinical phenotypes and their prognostic impact
por: Giacobbe, Daniele Roberto, et al.
Publicado: (2023)

Early Administration of Bamlanivimab in Combination with Etesevimab Increases the Benefits of COVID-19 Treatment: Real-World Experience from the Liguria Region
por: Vena, Antonio, et al.
Publicado: (2021)

Efficacy of Molnupiravir for the Treatment of Mild or Moderate COVID-19 in Adults: A Meta-Analysis
por: Benaicha, Karima, et al.
Publicado: (2023)

Short Course of Antifungal Therapy in Patients With Uncomplicated Candida Bloodstream Infection: Another Case of Less Is More in the Clinical Setting?
por: Vena, Antonio, et al.
Publicado: (2022)

Candida auris Candidemia in Critically Ill, Colonized Patients: Cumulative Incidence and Risk Factors
por: Briano, Federica, et al.
Publicado: (2022)

Treatment of Infections Due to MDR Gram-Negative Bacteria
por: Bassetti, Matteo, et al.
Publicado: (2019)

Challenges and research priorities to progress the impact of antimicrobial stewardship
por: Bassetti, Matteo, et al.
Publicado: (2019)

Mould Infections of Traumatic Wounds: A Brief Narrative Review
por: Giacobbe, Daniele Roberto, et al.
Publicado: (2020)

New antibiotics for the treatment of nonfermenting Gram-negative bacteria
por: Bassetti, Matteo, et al.
Publicado: (2021)

Ten Years of Medical Informatics and Standards Support for Clinical Research in an Infectious Diseases Network
por: Mora, Sara, et al.
Publicado: (2023)

Molecular Epidemiological Investigation of a Nosocomial Cluster of C. auris: Evidence of Recent Emergence in Italy and Ease of Transmission during the COVID-19 Pandemic
por: Di Pilato, Vincenzo, et al.
Publicado: (2021)

T2Bacteria and T2Resistance Assays in Critically Ill Patients with Sepsis or Septic Shock: A Descriptive Experience
por: Giacobbe, Daniele Roberto, et al.
Publicado: (2022)

Treatment of Bloodstream Infections Due to Gram-Negative Bacteria with Difficult-to-Treat Resistance
por: Bassetti, Matteo, et al.
Publicado: (2020)

A brief note on randomized controlled trials and compassionate/off-label use of drugs in the early phases of the COVID-19 pandemic
por: Bassetti, Matteo, et al.
Publicado: (2020)

Fidaxomicin for the Treatment of Clostridioides difficile Infection in Adult Patients: An Update on Results from Randomized Controlled Trials
por: Giacobbe, Daniele Roberto, et al.
Publicado: (2022)

Efficacy and Safety of Molnupiravir in Mild COVID-19 Patients in India
por: Sinha, Shubhadeep, et al.
Publicado: (2022)

Intermediate monocytes expansion and homing markers expression in COVID-19 patients associate with kidney dysfunction
por: Dentone, Chiara, et al.
Publicado: (2022)

Molnupiravir for treatment of adults with mild or moderate COVID-19: a systematic review and meta-analysis of randomized controlled trials
por: Gao, Ya, et al.
Publicado: (2023)

Kidney disease and all-cause mortality in patients with COVID-19 hospitalized in Genoa, Northern Italy
por: Russo, Elisa, et al.
Publicado: (2020)

Improving management and antimicrobial stewardship for bacterial and fungal infections in hospitalized patients with COVID-19
por: Peghin, Maddalena, et al.
Publicado: (2022)

Molnupiravir: From Hope to Epic Fail?
por: Focosi, Daniele
Publicado: (2022)

Sensitivity of Serum Beta-D-Glucan in Candidemia According to Candida Species Epidemiology in Critically Ill Patients Admitted to the Intensive Care Unit
por: Mikulska, Malgorzata, et al.
Publicado: (2022)

Real-world clinical outcomes of treatment with molnupiravir for patients with mild-to-moderate coronavirus disease 2019 during the Omicron variant pandemic
por: Suzuki, Yasuhito, et al.
Publicado: (2022)

Efficacy and safety of molnupiravir in patients with Omicron variant vaccine breakthrough COVID-19 infection: a randomized, controlled trial
por: Liu, Yayun, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_elmumeapn1j2tv2uh93ougosm5