SARS-CoV-2 Omicron Induces Enhanced Mucosal Interferon Response Compared to other Variants of Concern, Associated with Restricted Replication in Human Lung Tissues

SARS-CoV-2 Omicron variant has been characterized by decreased clinical severity, raising the question of whether early variant-specific interactions within the mucosal surfaces of the respiratory tract could mediate its attenuated pathogenicity. Here, we employed ex vivo infection of native human n...

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Detalles Bibliográficos
Autores principales: Alfi, Or, Hamdan, Marah, Wald, Ori, Yakirevitch, Arkadi, Wandel, Ori, Oiknine-Djian, Esther, Gvili, Ben, Knoller, Hadas, Rozendorn, Noa, Golan Berman, Hadar, Adar, Sheera, Vorontsov, Olesya, Mandelboim, Michal, Zakay-Rones, Zichria, Oberbaum, Menachem, Panet, Amos, Wolf, Dana G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318963/
https://www.ncbi.nlm.nih.gov/pubmed/35891570
http://dx.doi.org/10.3390/v14071583

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