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Flightless I Negatively Regulates Macrophage Surface TLR4, Delays Early Inflammation, and Impedes Wound Healing

TLR4 plays a pivotal role in orchestrating inflammation and tissue repair. Its expression has finally been balanced to initiate the early, robust immune response necessary for efficient repair without excessively amplifying and prolonging inflammation, which impairs healing. Studies show Flightless...

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Detalles Bibliográficos
Autores principales: Mills, Stuart J., Ahangar, Parinaz, Thomas, Hannah M., Hofma, Benjamin R., Murray, Rachael Z., Cowin, Allison J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318993/
https://www.ncbi.nlm.nih.gov/pubmed/35883634
http://dx.doi.org/10.3390/cells11142192