Cargando…

Flightless I Negatively Regulates Macrophage Surface TLR4, Delays Early Inflammation, and Impedes Wound Healing

TLR4 plays a pivotal role in orchestrating inflammation and tissue repair. Its expression has finally been balanced to initiate the early, robust immune response necessary for efficient repair without excessively amplifying and prolonging inflammation, which impairs healing. Studies show Flightless...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mills, Stuart J., Ahangar, Parinaz, Thomas, Hannah M., Hofma, Benjamin R., Murray, Rachael Z., Cowin, Allison J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9318993/ https://www.ncbi.nlm.nih.gov/pubmed/35883634 http://dx.doi.org/10.3390/cells11142192

Ejemplares similares

Attenuation of Flightless I Increases Human Pericyte Proliferation, Migration and Angiogenic Functions and Improves Healing in Murine Diabetic Wounds
por: Thomas, Hannah M, et al.
Publicado: (2020)

The Influence of Flightless I on Toll-Like-Receptor-Mediated Inflammation in a Murine Model of Diabetic Wound Healing
por: Ruzehaji, Nadira, et al.
Publicado: (2013)

Multifunctional Roles of the Actin-Binding Protein Flightless I in Inflammation, Cancer and Wound Healing
por: Strudwick, Xanthe L., et al.
Publicado: (2020)

Plasma-polymerized pericyte patches improve healing of murine wounds through increased angiogenesis and reduced inflammation
por: Thomas, Hannah M, et al.
Publicado: (2021)

Human gingival fibroblast secretome accelerates wound healing through anti-inflammatory and pro-angiogenic mechanisms
por: Ahangar, Parinaz, et al.
Publicado: (2020)

Mesenchymal Stem Cell Secretome as an Emerging Cell-Free Alternative for Improving Wound Repair
por: Ahangar, Parinaz, et al.
Publicado: (2020)

Reforming the Barrier: The Role of Formins in Wound Repair
por: Ahangar, Parinaz, et al.
Publicado: (2022)

Human multipotent adult progenitor cell-conditioned medium improves wound healing through modulating inflammation and angiogenesis in mice
por: Ahangar, Parinaz, et al.
Publicado: (2020)

The Importance of Pericytes in Healing: Wounds and other Pathologies
por: Thomas, Hannah M., et al.
Publicado: (2017)

Lysosomal secretion of Flightless I upon injury has the potential to alter inflammation
por: Cowin, Allison J., et al.
Publicado: (2012)

Recombinant Leucine-Rich Repeat Flightless-Interacting Protein-1 Improves Healing of Acute Wounds through Its Effects on Proliferation Inflammation and Collagen Deposition
por: Kopecki, Zlatko, et al.
Publicado: (2018)

Pericytes, Mesenchymal Stem Cells and the Wound Healing Process
por: Mills, Stuart J., et al.
Publicado: (2013)

Stem Cells for Cutaneous Wound Healing
por: Kirby, Giles T. S., et al.
Publicado: (2015)

Editorial: Inflammation in Healing and Regeneration of Cutaneous Wounds
por: Cowin, Allison J., et al.
Publicado: (2021)

Macrophage-Mediated Inflammation in Skin Wound Healing
por: Hassanshahi, Alireza, et al.
Publicado: (2022)

In vitro analysis of the effect of Flightless I on murine tenocyte cellular functions
por: Jackson, Jessica E., et al.
Publicado: (2020)

Development and use of biomaterials as wound healing therapies
por: Murray, Rachael Zoe, et al.
Publicado: (2019)

New Innovations in Wound Healing and Repair
por: Cowin, Allison J.
Publicado: (2019)

Delivery of multipotent adult progenitor cells via a functionalized plasma polymerized surface accelerates healing of murine diabetic wounds
por: Mills, S. J., et al.
Publicado: (2023)

Increasing the level of cytoskeletal protein Flightless I reduces adhesion formation in a murine digital flexor tendon model
por: Jackson, Jessica E., et al.
Publicado: (2020)

Flightless I Alters the Inflammatory Response and Autoantibody Profile in an OVA-Induced Atopic Dermatitis Skin-Like Disease
por: Kopecki, Zlatko, et al.
Publicado: (2018)

Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway
por: Yang, Gink N., et al.
Publicado: (2021)

Skin Wound Healing: Normal Macrophage Function and Macrophage Dysfunction in Diabetic Wounds
por: Aitcheson, Savannah M., et al.
Publicado: (2021)

Plasma-Functionalised Dressings for Enhanced Wound Healing
por: Strudwick, Xanthe L., et al.
Publicado: (2023)

Overexpression of Flii during Murine Embryonic Development Increases Symmetrical Division of Epidermal Progenitor Cells
por: Yang, Gink N., et al.
Publicado: (2021)

Influence of Acidic pH on Wound Healing In Vivo: A Novel Perspective for Wound Treatment
por: Sim, Pivian, et al.
Publicado: (2022)

Macrophage Phenotypes Regulate Scar Formation and Chronic Wound Healing
por: Hesketh, Mark, et al.
Publicado: (2017)

Anti‐β7 integrin treatment impedes the recruitment on non‐classical monocytes to the gut and delays macrophage‐mediated intestinal wound healing
por: Sommer, Katrin, et al.
Publicado: (2023)

Macrophage-Specific, Mafb-Deficient Mice Showed Delayed Skin Wound Healing
por: Inoue, Yuri, et al.
Publicado: (2022)

Flightless I exacerbation of inflammatory responses contributes to increased colonic damage in a mouse model of dextran sulphate sodium-induced ulcerative colitis
por: Kopecki, Z., et al.
Publicado: (2019)

Cytoskeletal protein flightless I inhibits apoptosis, enhances tumor cell invasion and promotes cutaneous squamous cell carcinoma progression
por: Kopecki, Zlatko, et al.
Publicado: (2015)

In Vitro Wound Healing Properties of Novel Acidic Treatment Regimen in Enhancing Metabolic Activity and Migration of Skin Cells
por: Sim, Pivian, et al.
Publicado: (2022)

Macrophages in Healing Wounds: Paradoxes and Paradigms
por: DiPietro, Luisa A., et al.
Publicado: (2021)

Eradication of Mature Bacterial Biofilms with Concurrent Improvement in Chronic Wound Healing Using Silver Nanoparticle Hydrogel Treatment
por: Haidari, Hanif, et al.
Publicado: (2021)

Age-Related Alterations in Macrophage Distribution and Function Are Associated With Delayed Cutaneous Wound Healing
por: Dube, Christabel Thembela, et al.
Publicado: (2022)

Diet-Induced Over-Expression of Flightless-I Protein and Its Relation to Flightlessness in Mediterranean Fruit Fly, Ceratitis capitata
por: Cho, Il Kyu, et al.
Publicado: (2013)

TLR4‐dependent shaping of the wound site by MSCs accelerates wound healing
por: Munir, Saira, et al.
Publicado: (2020)

Anthropogenic extinctions conceal widespread evolution of flightlessness in birds
por: Sayol, F., et al.
Publicado: (2020)

Flightless-I Controls Fat Storage in Drosophila
por: Park, Jung-Eun, et al.
Publicado: (2018)

Macrophage polarization in diabetic wound healing
por: Wu, Xingqian, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9ochknnd7m9sd1et7vrqk3dsjk