Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography

Aortic valve stenosis (AVS) is an increasingly prevalent disease in our aging population. Although multiple risk factors for AVS have been elucidated, medical therapies capable of slowing down disease progression remain unavailable. Molecular imaging technologies are opening up avenues for the non-i...

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Autores principales: Oostveen, Reindert F., Kaiser, Yannick, Stroes, Erik S.G., Verberne, Hein J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319069/
https://www.ncbi.nlm.nih.gov/pubmed/35890111
http://dx.doi.org/10.3390/ph15070812
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author Oostveen, Reindert F.
Kaiser, Yannick
Stroes, Erik S.G.
Verberne, Hein J.
author_facet Oostveen, Reindert F.
Kaiser, Yannick
Stroes, Erik S.G.
Verberne, Hein J.
author_sort Oostveen, Reindert F.
collection PubMed
description Aortic valve stenosis (AVS) is an increasingly prevalent disease in our aging population. Although multiple risk factors for AVS have been elucidated, medical therapies capable of slowing down disease progression remain unavailable. Molecular imaging technologies are opening up avenues for the non-invasive assessment of disease progression, allowing the assessment of (early) medical interventions. This review will focus on the role of positron emission tomography of the aortic valve with (18)F-fluorodeoxyglucose and (18)F-sodium fluoride but will also shed light on novel tracers which have potential in AVS, ranging from the healthy aortic valve to end-stage valvular disease.
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spelling pubmed-93190692022-07-27 Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography Oostveen, Reindert F. Kaiser, Yannick Stroes, Erik S.G. Verberne, Hein J. Pharmaceuticals (Basel) Review Aortic valve stenosis (AVS) is an increasingly prevalent disease in our aging population. Although multiple risk factors for AVS have been elucidated, medical therapies capable of slowing down disease progression remain unavailable. Molecular imaging technologies are opening up avenues for the non-invasive assessment of disease progression, allowing the assessment of (early) medical interventions. This review will focus on the role of positron emission tomography of the aortic valve with (18)F-fluorodeoxyglucose and (18)F-sodium fluoride but will also shed light on novel tracers which have potential in AVS, ranging from the healthy aortic valve to end-stage valvular disease. MDPI 2022-06-30 /pmc/articles/PMC9319069/ /pubmed/35890111 http://dx.doi.org/10.3390/ph15070812 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Oostveen, Reindert F.
Kaiser, Yannick
Stroes, Erik S.G.
Verberne, Hein J.
Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography
title Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography
title_full Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography
title_fullStr Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography
title_full_unstemmed Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography
title_short Molecular Imaging of Aortic Valve Stenosis with Positron Emission Tomography
title_sort molecular imaging of aortic valve stenosis with positron emission tomography
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319069/
https://www.ncbi.nlm.nih.gov/pubmed/35890111
http://dx.doi.org/10.3390/ph15070812
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