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A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia

A large number of reports present artificial intelligence (AI) algorithms, which support pneumonia detection caused by COVID-19 from chest CT (computed tomography) scans. Only a few studies provided access to the source code, which limits the analysis of the out-of-distribution generalization abilit...

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Autores principales: Furtado, Adhvan, da Purificação, Carlos Alberto Campos, Badaró, Roberto, Nascimento, Erick Giovani Sperandio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319098/
https://www.ncbi.nlm.nih.gov/pubmed/35885433
http://dx.doi.org/10.3390/diagnostics12071527
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author Furtado, Adhvan
da Purificação, Carlos Alberto Campos
Badaró, Roberto
Nascimento, Erick Giovani Sperandio
author_facet Furtado, Adhvan
da Purificação, Carlos Alberto Campos
Badaró, Roberto
Nascimento, Erick Giovani Sperandio
author_sort Furtado, Adhvan
collection PubMed
description A large number of reports present artificial intelligence (AI) algorithms, which support pneumonia detection caused by COVID-19 from chest CT (computed tomography) scans. Only a few studies provided access to the source code, which limits the analysis of the out-of-distribution generalization ability. This study presents Cimatec-CovNet-19, a new light 3D convolutional neural network inspired by the VGG16 architecture that supports COVID-19 identification from chest CT scans. We trained the algorithm with a dataset of 3000 CT Scans (1500 COVID-19-positive) with images from different parts of the world, enhanced with 3000 images obtained with data augmentation techniques. We introduced a novel pre-processing approach to perform a slice-wise selection based solely on the lung CT masks and an empirically chosen threshold for the very first slice. It required only 16 slices from a CT examination to identify COVID-19. The model achieved a recall of 0.88, specificity of 0.88, ROC-AUC of 0.95, PR-AUC of 0.95, and F1-score of 0.88 on a test set with 414 samples (207 COVID-19). These results support Cimatec-CovNet-19 as a good and light screening tool for COVID-19 patients. The whole code is freely available for the scientific community.
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spelling pubmed-93190982022-07-27 A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia Furtado, Adhvan da Purificação, Carlos Alberto Campos Badaró, Roberto Nascimento, Erick Giovani Sperandio Diagnostics (Basel) Article A large number of reports present artificial intelligence (AI) algorithms, which support pneumonia detection caused by COVID-19 from chest CT (computed tomography) scans. Only a few studies provided access to the source code, which limits the analysis of the out-of-distribution generalization ability. This study presents Cimatec-CovNet-19, a new light 3D convolutional neural network inspired by the VGG16 architecture that supports COVID-19 identification from chest CT scans. We trained the algorithm with a dataset of 3000 CT Scans (1500 COVID-19-positive) with images from different parts of the world, enhanced with 3000 images obtained with data augmentation techniques. We introduced a novel pre-processing approach to perform a slice-wise selection based solely on the lung CT masks and an empirically chosen threshold for the very first slice. It required only 16 slices from a CT examination to identify COVID-19. The model achieved a recall of 0.88, specificity of 0.88, ROC-AUC of 0.95, PR-AUC of 0.95, and F1-score of 0.88 on a test set with 414 samples (207 COVID-19). These results support Cimatec-CovNet-19 as a good and light screening tool for COVID-19 patients. The whole code is freely available for the scientific community. MDPI 2022-06-23 /pmc/articles/PMC9319098/ /pubmed/35885433 http://dx.doi.org/10.3390/diagnostics12071527 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Furtado, Adhvan
da Purificação, Carlos Alberto Campos
Badaró, Roberto
Nascimento, Erick Giovani Sperandio
A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia
title A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia
title_full A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia
title_fullStr A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia
title_full_unstemmed A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia
title_short A Light Deep Learning Algorithm for CT Diagnosis of COVID-19 Pneumonia
title_sort light deep learning algorithm for ct diagnosis of covid-19 pneumonia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319098/
https://www.ncbi.nlm.nih.gov/pubmed/35885433
http://dx.doi.org/10.3390/diagnostics12071527
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