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Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease

Single ventricle (SV) heart disease comprises a spectrum of complex congenital heart defects (CHDs), including hypoplastic left heart syndrome (HLHS), one of the most common causes of death amongst infants with CHD. Despite its incompletely defined etiology and a dearth of curative solutions, SV is...

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Detalles Bibliográficos
Autores principales: Davis, Kaitlin A., Pickles, Diane M., Keller, Kirstie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319216/
https://www.ncbi.nlm.nih.gov/pubmed/35877582
http://dx.doi.org/10.3390/jcdd9070220
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author Davis, Kaitlin A.
Pickles, Diane M.
Keller, Kirstie E.
author_facet Davis, Kaitlin A.
Pickles, Diane M.
Keller, Kirstie E.
author_sort Davis, Kaitlin A.
collection PubMed
description Single ventricle (SV) heart disease comprises a spectrum of complex congenital heart defects (CHDs), including hypoplastic left heart syndrome (HLHS), one of the most common causes of death amongst infants with CHD. Despite its incompletely defined etiology and a dearth of curative solutions, SV is a solvable problem that can be addressed by unifying a nascent field that is ripe for investment, in part due to its high economic impact and growth potential. Here, we explore the landscape of SV and identify areas of opportunity that will yield an outsized impact through strategic investment that focuses on synchronization across disciplines, community involvement, and infrastructure development, and argue that nonprofits are the appropriate catalyst to spark transformative innovation and impact in the form of functional cures.
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spelling pubmed-93192162022-07-27 Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease Davis, Kaitlin A. Pickles, Diane M. Keller, Kirstie E. J Cardiovasc Dev Dis Editorial Single ventricle (SV) heart disease comprises a spectrum of complex congenital heart defects (CHDs), including hypoplastic left heart syndrome (HLHS), one of the most common causes of death amongst infants with CHD. Despite its incompletely defined etiology and a dearth of curative solutions, SV is a solvable problem that can be addressed by unifying a nascent field that is ripe for investment, in part due to its high economic impact and growth potential. Here, we explore the landscape of SV and identify areas of opportunity that will yield an outsized impact through strategic investment that focuses on synchronization across disciplines, community involvement, and infrastructure development, and argue that nonprofits are the appropriate catalyst to spark transformative innovation and impact in the form of functional cures. MDPI 2022-07-08 /pmc/articles/PMC9319216/ /pubmed/35877582 http://dx.doi.org/10.3390/jcdd9070220 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Editorial
Davis, Kaitlin A.
Pickles, Diane M.
Keller, Kirstie E.
Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease
title Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease
title_full Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease
title_fullStr Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease
title_full_unstemmed Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease
title_short Catalysts for Change: The Role of Nonprofits in Solving Single Ventricle Heart Disease
title_sort catalysts for change: the role of nonprofits in solving single ventricle heart disease
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319216/
https://www.ncbi.nlm.nih.gov/pubmed/35877582
http://dx.doi.org/10.3390/jcdd9070220
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