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Hereditary Diffuse Gastric Cancer: Molecular Genetics, Biological Mechanisms and Current Therapeutic Approaches

Hereditary diffuse gastric cancer is an autosomal dominant syndrome characterized by a high prevalence of diffuse gastric cancer and lobular breast cancer. It is caused by inactivating mutations in the tumor suppressor gene CDH1. Genetic testing technologies have become more efficient over the years...

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Detalles Bibliográficos
Autores principales:	Cosma, Lidia-Sabina, Schlosser, Sophie, Tews, Hauke C., Müller, Martina, Kandulski, Arne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319245/ https://www.ncbi.nlm.nih.gov/pubmed/35887173 http://dx.doi.org/10.3390/ijms23147821

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