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Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018

Pediatric tuberculosis is a serious infectious disease and a hidden global epidemic. The objective of this study was to describe the epidemiological situation of tuberculosis mortality in children under 15 years of age in Colombia in the period 2010–2018. A longitudinal descriptive study was conduct...

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Autores principales: Plata-Casas, Laura, González-Támara, Leandro, Cala-Vitery, Favio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319292/
https://www.ncbi.nlm.nih.gov/pubmed/35878129
http://dx.doi.org/10.3390/tropicalmed7070117
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author Plata-Casas, Laura
González-Támara, Leandro
Cala-Vitery, Favio
author_facet Plata-Casas, Laura
González-Támara, Leandro
Cala-Vitery, Favio
author_sort Plata-Casas, Laura
collection PubMed
description Pediatric tuberculosis is a serious infectious disease and a hidden global epidemic. The objective of this study was to describe the epidemiological situation of tuberculosis mortality in children under 15 years of age in Colombia in the period 2010–2018. A longitudinal descriptive study was conducted. The variables sex, age groups, and origin were studied. This study had 260 cases for analysis and was carried out in three phases. The first phase was the determination of the sociodemographic and clinical characteristics. The second phase was the construction of indicators by territorial entities. The third phase was stratification into four epidemiological situations according to the mortality rate and years of life lost. The median age was 7 years (range 0–14), 66.5% of cases were pulmonary tuberculosis (97.7% without bacteriological confirmation), 14.3781 years of life lost were recorded (95% CI: 142.811–168.333), and in children under 10–14 years, the loss was 110,057. Amazonas had the highest adjusted YLL rate (3979.7). In total, 36.4% of the territories had a high mortality, and 30.3% adjusted to the situation designated as 1. This is the first study that has used composite indicators to address the problem of premature mortality from childhood tuberculosis in Colombia. Our results allow us to specify that this disease remains a challenge for public health. It requires models of care and differential strategies by region. It also requires ensuring opportunities in diagnosis with sensitive methods, as well as intersectoral work for the optimal approach.
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spelling pubmed-93192922022-07-27 Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018 Plata-Casas, Laura González-Támara, Leandro Cala-Vitery, Favio Trop Med Infect Dis Article Pediatric tuberculosis is a serious infectious disease and a hidden global epidemic. The objective of this study was to describe the epidemiological situation of tuberculosis mortality in children under 15 years of age in Colombia in the period 2010–2018. A longitudinal descriptive study was conducted. The variables sex, age groups, and origin were studied. This study had 260 cases for analysis and was carried out in three phases. The first phase was the determination of the sociodemographic and clinical characteristics. The second phase was the construction of indicators by territorial entities. The third phase was stratification into four epidemiological situations according to the mortality rate and years of life lost. The median age was 7 years (range 0–14), 66.5% of cases were pulmonary tuberculosis (97.7% without bacteriological confirmation), 14.3781 years of life lost were recorded (95% CI: 142.811–168.333), and in children under 10–14 years, the loss was 110,057. Amazonas had the highest adjusted YLL rate (3979.7). In total, 36.4% of the territories had a high mortality, and 30.3% adjusted to the situation designated as 1. This is the first study that has used composite indicators to address the problem of premature mortality from childhood tuberculosis in Colombia. Our results allow us to specify that this disease remains a challenge for public health. It requires models of care and differential strategies by region. It also requires ensuring opportunities in diagnosis with sensitive methods, as well as intersectoral work for the optimal approach. MDPI 2022-06-25 /pmc/articles/PMC9319292/ /pubmed/35878129 http://dx.doi.org/10.3390/tropicalmed7070117 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Plata-Casas, Laura
González-Támara, Leandro
Cala-Vitery, Favio
Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018
title Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018
title_full Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018
title_fullStr Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018
title_full_unstemmed Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018
title_short Tuberculosis Mortality in Children under Fifteen Years of Age: Epidemiological Situation in Colombia, 2010–2018
title_sort tuberculosis mortality in children under fifteen years of age: epidemiological situation in colombia, 2010–2018
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319292/
https://www.ncbi.nlm.nih.gov/pubmed/35878129
http://dx.doi.org/10.3390/tropicalmed7070117
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