RIPpore: A Novel Host-Derived Method for the Identification of Ricin Intoxication through Oxford Nanopore Direct RNA Sequencing

Ricin is a toxin which enters cells and depurinates an adenine base in the sarcin-ricin loop in the large ribosomal subunit, leading to the inhibition of protein translation and cell death. We postulated that this depurination event could be detected using Oxford Nanopore Technologies (ONT) direct R...

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Detalles Bibliográficos
Autores principales: Ryan, Yan, Harrison, Abbie, Trivett, Hannah, Hartley, Catherine, David, Jonathan, Clark, Graeme C., Hiscox, Julian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319349/
https://www.ncbi.nlm.nih.gov/pubmed/35878208
http://dx.doi.org/10.3390/toxins14070470

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