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A Comprehensive Study to Identify Major Metabolites of an Amoxicillin–Sulbactam Hybrid Molecule in Rats and Its Metabolic Pathway Using UPLC-Q-TOF-MS/MS

Amoxicillin and sulbactam are widely used compound drugs in animal food. The amoxicillin–sulbactam hybrid molecule can achieve better curative effects through the combination of the two drugs. However, its pharmacokinetic behavior needs to be explored. In this study, a randomized crossover experimen...

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Detalles Bibliográficos
Autores principales: Zhao, Fei-Ke, Shi, Ren-Bin, Sun, Yu-Bin, Yang, Shuang-Yun, Chen, Liang-Zhu, Fang, Bing-Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319383/
https://www.ncbi.nlm.nih.gov/pubmed/35888786
http://dx.doi.org/10.3390/metabo12070662