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Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury

The objective of this study was to analyze the factors affecting the instant recovery of neurological function in patients with motor complete traumatic spinal cord injury (TSCI) treated in hospital. Methods: A retrospective analysis of 1053 patients with TSCI classified according to the American Sp...

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Autores principales: Gao, Xiangcheng, Gong, Yining, Zhang, Bo, Hao, Dingjun, He, Baorong, Yan, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319428/
https://www.ncbi.nlm.nih.gov/pubmed/35887845
http://dx.doi.org/10.3390/jcm11144086
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author Gao, Xiangcheng
Gong, Yining
Zhang, Bo
Hao, Dingjun
He, Baorong
Yan, Liang
author_facet Gao, Xiangcheng
Gong, Yining
Zhang, Bo
Hao, Dingjun
He, Baorong
Yan, Liang
author_sort Gao, Xiangcheng
collection PubMed
description The objective of this study was to analyze the factors affecting the instant recovery of neurological function in patients with motor complete traumatic spinal cord injury (TSCI) treated in hospital. Methods: A retrospective analysis of 1053 patients with TSCI classified according to the American Spinal Cord Injury Association (ASIA) as grades A and B at 59 tertiary hospitals from 1 January 2018 to 31 December 2018 was performed. All patients were classified into motor complete injury (ASIA A or B) and motor incomplete injury (ASIA C or D) groups, according to the ASIA upon discharge. The injury level, fracture segment, fracture type, ASIA score at admission and discharge, treatment protocol, and complications were recorded. Univariate and multivariate analyses were performed to evaluate the relationship between various factors and the recovery of neurological function. Results: The results of multiple logistic regression analysis revealed that the ASIA score on admission (p < 0.001, odds ratio (OR) = 5.722, 95% confidence interval (CI): 4.147–7.895), fracture or dislocation (p = 0.001, OR = 0.523, 95% CI: 0.357–0.767), treatment protocol (p < 0.001; OR = 2.664, 95% CI: 1.689–4.203), and inpatient rehabilitation (p < 0.001, OR = 2.089, 95% CI: 1.501–2.909) were independently associated with the recovery of neurological function. Conclusion: The recovery of neurological function is dependent on the ASIA score on admission, fracture or dislocation, treatment protocol, and inpatient rehabilitation.
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spelling pubmed-93194282022-07-27 Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury Gao, Xiangcheng Gong, Yining Zhang, Bo Hao, Dingjun He, Baorong Yan, Liang J Clin Med Article The objective of this study was to analyze the factors affecting the instant recovery of neurological function in patients with motor complete traumatic spinal cord injury (TSCI) treated in hospital. Methods: A retrospective analysis of 1053 patients with TSCI classified according to the American Spinal Cord Injury Association (ASIA) as grades A and B at 59 tertiary hospitals from 1 January 2018 to 31 December 2018 was performed. All patients were classified into motor complete injury (ASIA A or B) and motor incomplete injury (ASIA C or D) groups, according to the ASIA upon discharge. The injury level, fracture segment, fracture type, ASIA score at admission and discharge, treatment protocol, and complications were recorded. Univariate and multivariate analyses were performed to evaluate the relationship between various factors and the recovery of neurological function. Results: The results of multiple logistic regression analysis revealed that the ASIA score on admission (p < 0.001, odds ratio (OR) = 5.722, 95% confidence interval (CI): 4.147–7.895), fracture or dislocation (p = 0.001, OR = 0.523, 95% CI: 0.357–0.767), treatment protocol (p < 0.001; OR = 2.664, 95% CI: 1.689–4.203), and inpatient rehabilitation (p < 0.001, OR = 2.089, 95% CI: 1.501–2.909) were independently associated with the recovery of neurological function. Conclusion: The recovery of neurological function is dependent on the ASIA score on admission, fracture or dislocation, treatment protocol, and inpatient rehabilitation. MDPI 2022-07-14 /pmc/articles/PMC9319428/ /pubmed/35887845 http://dx.doi.org/10.3390/jcm11144086 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gao, Xiangcheng
Gong, Yining
Zhang, Bo
Hao, Dingjun
He, Baorong
Yan, Liang
Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury
title Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury
title_full Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury
title_fullStr Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury
title_full_unstemmed Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury
title_short Factors for Predicting Instant Neurological Recovery of Patients with Motor Complete Traumatic Spinal Cord Injury
title_sort factors for predicting instant neurological recovery of patients with motor complete traumatic spinal cord injury
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319428/
https://www.ncbi.nlm.nih.gov/pubmed/35887845
http://dx.doi.org/10.3390/jcm11144086
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