Characterization of Domiphen Bromide as a New Fast-Acting Antiplasmodial Agent Inhibiting the Apicoplastidic Methyl Erythritol Phosphate Pathway

The evolution of resistance by the malaria parasite to artemisinin, the key component of the combination therapy strategies that are at the core of current antimalarial treatments, calls for the urgent identification of new fast-acting antimalarials. The apicoplast organelle is a preferred target of...

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Detalles Bibliográficos
Autores principales: Biosca, Arnau, Ramírez, Miriam, Gomez-Gomez, Alex, Lafuente, Aritz, Iglesias, Valentín, Pozo, Oscar J., Imperial, Santiago, Fernàndez-Busquets, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319574/
https://www.ncbi.nlm.nih.gov/pubmed/35890216
http://dx.doi.org/10.3390/pharmaceutics14071320

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319574/
https://www.ncbi.nlm.nih.gov/pubmed/35890216
http://dx.doi.org/10.3390/pharmaceutics14071320

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