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Saporin Toxin Delivered by Engineered Colloidal Nanoparticles Is Strongly Effective against Cancer Cells

Ribosome-inactivating proteins, including Saporin toxin, have found application in the search for innovative alternative cancer therapies to conventional chemo- and radiotherapy. Saporin’s main mechanism of action involves the inhibition of cytoplasmic protein synthesis. Its strong theoretical effic...

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Detalles Bibliográficos
Autores principales: Salvioni, Lucia, Testa, Filippo, Barbieri, Linda, Giustra, Marco, Bertolini, Jessica Armida, Tomaino, Giulia, Tortora, Paolo, Prosperi, Davide, Colombo, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319684/
https://www.ncbi.nlm.nih.gov/pubmed/35890411
http://dx.doi.org/10.3390/pharmaceutics14071517