A Novel ERK2 Degrader Z734 Induces Apoptosis of MCF–7 Cells via the HERC3/p53 Signaling Pathway

Breast cancer is one of the leading causes of death worldwide, and synthetic chemicals targeting specific proteins or various molecular pathways for tumor suppression, such as ERK inhibitors and degraders, have been intensively investigated. The targets of ERK participate in the regulation of critic...

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Detalles Bibliográficos
Autores principales: Xu, Shiyao, Xiong, Yan, Yao, Rui, Tian, Rong, Meng, Zhuqing, Zaky, Mohamed Y., Fu, Beibei, Guo, Dong, Wang, Lulu, Lin, Feng, Lin, Xiaoyuan, Wu, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319741/
https://www.ncbi.nlm.nih.gov/pubmed/35889210
http://dx.doi.org/10.3390/molecules27144337

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