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Homo and Heterotypic Cellular Cross-Talk in Epithelial Ovarian Cancer Impart Pro-Tumorigenic Properties through Differential Activation of the Notch3 Pathway

SIMPLE SUMMARY: The omental metastatic spreading of epithelial ovarian cancer is spearheaded by complex cell–cell interactions present in the fluidic microenvironment (ascites), which is yet to be fully decoded. Using a unique co-culture model of SNFT (SKOV3 cells expressing a Notch3 luciferase repo...

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Detalles Bibliográficos
Autores principales: Mukherjee, Souvik, Sakpal, Asmita, Mehrotra, Megha, Phadte, Pratham, Rekhi, Bharat, Ray, Pritha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319742/
https://www.ncbi.nlm.nih.gov/pubmed/35884426
http://dx.doi.org/10.3390/cancers14143365