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The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections

The spread of viral diseases has caused global concern in recent years. Detecting viral infections has become challenging in medical research due to their high infectivity and mutation. A rapid and accurate detection method in biomedical and healthcare segments is essential for the effective treatme...

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Autores principales: Mousavi, Seyyed Mojtaba, Hashemi, Seyyed Alireza, Yari Kalashgrani, Masoomeh, Omidifar, Navid, Lai, Chin Wei, Vijayakameswara Rao, Neralla, Gholami, Ahmad, Chiang, Wei-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319763/
https://www.ncbi.nlm.nih.gov/pubmed/35890178
http://dx.doi.org/10.3390/ph15070880
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author Mousavi, Seyyed Mojtaba
Hashemi, Seyyed Alireza
Yari Kalashgrani, Masoomeh
Omidifar, Navid
Lai, Chin Wei
Vijayakameswara Rao, Neralla
Gholami, Ahmad
Chiang, Wei-Hung
author_facet Mousavi, Seyyed Mojtaba
Hashemi, Seyyed Alireza
Yari Kalashgrani, Masoomeh
Omidifar, Navid
Lai, Chin Wei
Vijayakameswara Rao, Neralla
Gholami, Ahmad
Chiang, Wei-Hung
author_sort Mousavi, Seyyed Mojtaba
collection PubMed
description The spread of viral diseases has caused global concern in recent years. Detecting viral infections has become challenging in medical research due to their high infectivity and mutation. A rapid and accurate detection method in biomedical and healthcare segments is essential for the effective treatment of pathogenic viruses and early detection of these viruses. Biosensors are used worldwide to detect viral infections associated with the molecular detection of biomarkers. Thus, detecting viruses based on quantum dots biomarkers is inexpensive and has great potential. To detect the ultrasensitive biomarkers of viral infections, QDs appear to be a promising option as biological probes, while physiological components have been used directly to detect multiple biomarkers simultaneously. The simultaneous measurement of numerous clinical parameters of the same sample volume is possible through multiplex detection of human viral infections, which reduces the time and cost required to record any data point. The purpose of this paper is to review recent studies on the effectiveness of the quantum dot as a detection tool for human pandemic viruses. In this review study, different types of quantum dots and their valuable properties in the structure of biomarkers were investigated. Finally, a vision for recent advances in quantum dot-based biomarkers was presented, whereby they can be integrated into super-sensitive probes for the multiplex detection of human viral infections.
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spelling pubmed-93197632022-07-27 The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections Mousavi, Seyyed Mojtaba Hashemi, Seyyed Alireza Yari Kalashgrani, Masoomeh Omidifar, Navid Lai, Chin Wei Vijayakameswara Rao, Neralla Gholami, Ahmad Chiang, Wei-Hung Pharmaceuticals (Basel) Review The spread of viral diseases has caused global concern in recent years. Detecting viral infections has become challenging in medical research due to their high infectivity and mutation. A rapid and accurate detection method in biomedical and healthcare segments is essential for the effective treatment of pathogenic viruses and early detection of these viruses. Biosensors are used worldwide to detect viral infections associated with the molecular detection of biomarkers. Thus, detecting viruses based on quantum dots biomarkers is inexpensive and has great potential. To detect the ultrasensitive biomarkers of viral infections, QDs appear to be a promising option as biological probes, while physiological components have been used directly to detect multiple biomarkers simultaneously. The simultaneous measurement of numerous clinical parameters of the same sample volume is possible through multiplex detection of human viral infections, which reduces the time and cost required to record any data point. The purpose of this paper is to review recent studies on the effectiveness of the quantum dot as a detection tool for human pandemic viruses. In this review study, different types of quantum dots and their valuable properties in the structure of biomarkers were investigated. Finally, a vision for recent advances in quantum dot-based biomarkers was presented, whereby they can be integrated into super-sensitive probes for the multiplex detection of human viral infections. MDPI 2022-07-17 /pmc/articles/PMC9319763/ /pubmed/35890178 http://dx.doi.org/10.3390/ph15070880 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Mousavi, Seyyed Mojtaba
Hashemi, Seyyed Alireza
Yari Kalashgrani, Masoomeh
Omidifar, Navid
Lai, Chin Wei
Vijayakameswara Rao, Neralla
Gholami, Ahmad
Chiang, Wei-Hung
The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections
title The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections
title_full The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections
title_fullStr The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections
title_full_unstemmed The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections
title_short The Pivotal Role of Quantum Dots-Based Biomarkers Integrated with Ultra-Sensitive Probes for Multiplex Detection of Human Viral Infections
title_sort pivotal role of quantum dots-based biomarkers integrated with ultra-sensitive probes for multiplex detection of human viral infections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319763/
https://www.ncbi.nlm.nih.gov/pubmed/35890178
http://dx.doi.org/10.3390/ph15070880
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