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Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage

Parthanatos is programmed cell death mediated by poly(ADP-ribose) polymerase 1 (PARP1) after DNA damage. PARP1 acts by catalyzing the transfer of poly(ADP-ribose) (PAR) polymers to various nuclear proteins. PAR is subsequently cleaved, generating protein-free PAR polymers, which are translocated to...

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Detalles Bibliográficos
Autores principales:	Mashimo, Masato, Morozumi, Akane, Nobeyama, Akari, Kanzaki, Misato, Negi, Shigeru, Kato, Jiro, Moss, Joel, Nomura, Atsuo, Fujii, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319841/ https://www.ncbi.nlm.nih.gov/pubmed/35887176 http://dx.doi.org/10.3390/ijms23147827

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