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Preclinical Development of a Therapy for Chronic Traumatic Spinal Cord Injury in Rats Using Human Wharton’s Jelly Mesenchymal Stromal Cells: Proof of Concept and Regulatory Compliance
(1) Background: the use of Mesenchymal Stromal Cells (MSC) in emerging therapies for spinal cord injury (SCI) hold the potential to improve functional recovery. However, the development of cell-based medicines is challenging and preclinical studies addressing quality, safety and efficacy must be con...
Autores principales: | Vives, Joaquim, Hernández, Joaquim, Mirabel, Clémentine, Puigdomenech-Poch, Maria, Romeo-Guitart, David, Marmolejo-Martínez-Artesero, Sara, Cabrera-Pérez, Raquel, Jaramillo, Jessica, Kumru, Hatice, García-López, Joan, Vidal-Samsó, Joan, Navarro, Xavier, Coll-Bonet, Ruth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9319990/ https://www.ncbi.nlm.nih.gov/pubmed/35883596 http://dx.doi.org/10.3390/cells11142153 |
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