Development and Applications of a Zebrafish (Danio rerio) CYP1A-Targeted Monoclonal Antibody (CRC4) with Reactivity across Vertebrate Taxa: Evidence for a Conserved CYP1A Epitope

CYP1A is a heme-thiolate enzyme associated with the cytochrome P4501A1 monooxygenase system and is inducible by a wide variety of xenobiotics and endogenous ligands that bind and activate the aryl hydrocarbon receptor (AHR). The AHR-CYP1A axis is important for detoxification of certain xenobiotics a...

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Detalles Bibliográficos
Autores principales: Anderson, Amy L., Dubanksy, Benjamin D., Wilson, Lindsay B., Tanguay, Robyn L., Rice, Charles D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320060/
https://www.ncbi.nlm.nih.gov/pubmed/35878309
http://dx.doi.org/10.3390/toxics10070404

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