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Linolenic Acid Plus Ethanol Exacerbates Cell Death in Saccharomyces cerevisiae by Promoting Lipid Peroxidation, Cardiolipin Loss, and Necrosis

Polyunsaturated fatty acids (PUFA) hypersensitize yeast to oxidative stress. Ethanol accumulation during fermentation is another factor that induces oxidative stress via mitochondrial dysfunction and ROS overproduction. Since this microorganism has raised growing interest as a PUFA factory, we have...

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Detalles Bibliográficos
Autores principales: Olmos-Orizaba, Berenice Eridani, Arroyo-Peñaloza, José Santos, Martínez-Alcántar, Lorena, Montoya-Pérez, Rocío, Flores-García, Alberto, Rodríguez-Orozco, Alain Raimundo, Calderón-Cortés, Elizabeth, Saavedra-Molina, Alfredo, Campos-García, Jesús, Cortés-Rojo, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320082/
https://www.ncbi.nlm.nih.gov/pubmed/35888140
http://dx.doi.org/10.3390/life12071052