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Linolenic Acid Plus Ethanol Exacerbates Cell Death in Saccharomyces cerevisiae by Promoting Lipid Peroxidation, Cardiolipin Loss, and Necrosis
Polyunsaturated fatty acids (PUFA) hypersensitize yeast to oxidative stress. Ethanol accumulation during fermentation is another factor that induces oxidative stress via mitochondrial dysfunction and ROS overproduction. Since this microorganism has raised growing interest as a PUFA factory, we have...
Autores principales: | Olmos-Orizaba, Berenice Eridani, Arroyo-Peñaloza, José Santos, Martínez-Alcántar, Lorena, Montoya-Pérez, Rocío, Flores-García, Alberto, Rodríguez-Orozco, Alain Raimundo, Calderón-Cortés, Elizabeth, Saavedra-Molina, Alfredo, Campos-García, Jesús, Cortés-Rojo, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320082/ https://www.ncbi.nlm.nih.gov/pubmed/35888140 http://dx.doi.org/10.3390/life12071052 |
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