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Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration

OBJECTIVE(S): Lysine-specific demethylase1 (LSD1), an important class of histone demethylases, plays a crucial role in regulation of mammalian biology. The up-regulated LSD1 expression was frequently associated with progress and oncogenesis of multiple human cancers, including non-small cell lung ca...

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Detalles Bibliográficos
Autores principales: Qin, Ting-ting, Li, Zhong-hua, Li, Li-xin, Du, Kun, Yang, Ji-ge, Zhang, Zhen-qiang, Wu, Xiang-xiang, Ma, Jin-lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320206/
https://www.ncbi.nlm.nih.gov/pubmed/35949313
http://dx.doi.org/10.22038/IJBMS.2022.62541.13851