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Sanguinarine, identified as a natural alkaloid LSD1 inhibitor, suppresses lung cancer cell growth and migration
OBJECTIVE(S): Lysine-specific demethylase1 (LSD1), an important class of histone demethylases, plays a crucial role in regulation of mammalian biology. The up-regulated LSD1 expression was frequently associated with progress and oncogenesis of multiple human cancers, including non-small cell lung ca...
Autores principales: | Qin, Ting-ting, Li, Zhong-hua, Li, Li-xin, Du, Kun, Yang, Ji-ge, Zhang, Zhen-qiang, Wu, Xiang-xiang, Ma, Jin-lian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320206/ https://www.ncbi.nlm.nih.gov/pubmed/35949313 http://dx.doi.org/10.22038/IJBMS.2022.62541.13851 |
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