Cargando…

Hedgehog Signaling in CNS Remyelination

Remyelination is a fundamental repair process in the central nervous system (CNS) that is triggered by demyelinating events. In demyelinating diseases, oligodendrocytes (OLs) are targeted, leading to myelin loss, axonal damage, and severe functional impairment. While spontaneous remyelination often...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fang, Minxi, Tang, Tao, Qiu, Mengsheng, Xu, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320235/ https://www.ncbi.nlm.nih.gov/pubmed/35883703 http://dx.doi.org/10.3390/cells11142260

Ejemplares similares

Astrocyte Regulation of CNS Inflammation and Remyelination
por: Claycomb, Kumiko I., et al.
Publicado: (2013)

The Current Challenges for Drug Discovery in CNS Remyelination
por: Balestri, Sonia, et al.
Publicado: (2021)

CNS Remyelination and the Innate Immune System
por: McMurran, Christopher E., et al.
Publicado: (2016)

Baicalin Promotes CNS Remyelination via PPARγ Signal Pathway
por: Ai, Ruo-Song, et al.
Publicado: (2022)

Emerging Cellular and Molecular Strategies for Enhancing Central Nervous System (CNS) Remyelination
por: Abu-Rub, Mohammad, et al.
Publicado: (2018)

CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
por: Dimas, Penelope, et al.
Publicado: (2019)

What roles do growth factors play in CNS remyelination?
por: Franklin, Robin J.M., et al.
Publicado: (2001)

Utilizing mouse optic nerve crush to examine CNS remyelination
por: Suter, Tracey A.C.S., et al.
Publicado: (2021)

Transcriptomic atlas and interaction networks of brain cells in mouse CNS demyelination and remyelination
por: Hou, Jinchao, et al.
Publicado: (2023)

Tracking the evolution of CNS remyelinating lesion in mice with neutral red dye
por: Baydyuk, Maryna, et al.
Publicado: (2019)

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination
por: De La Fuente, Alerie Guzman, et al.
Publicado: (2017)

Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
por: Neumann, Björn, et al.
Publicado: (2019)

Prolonging the integrated stress response enhances CNS remyelination in an inflammatory environment
por: Chen, Yanan, et al.
Publicado: (2021)

Nalfurafine reduces neuroinflammation and drives remyelination in models of CNS demyelinating disease
por: Denny, Lisa, et al.
Publicado: (2021)

EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP, and senescence pathways
por: Wang, Jiajia, et al.
Publicado: (2020)

Glial response during cuprizone-induced de- and remyelination in the CNS: lessons learned
por: Gudi, Viktoria, et al.
Publicado: (2014)

Chd7 Cooperates with Sox10 and Regulates the Onset of CNS Myelination and Remyelination
por: He, Danyang, et al.
Publicado: (2016)

The choline pathway as a strategy to promote central nervous system (CNS) remyelination
por: Skripuletz, Thomas, et al.
Publicado: (2015)

Tuftsin Combines With Remyelinating Therapy and Improves Outcomes in Models of CNS Demyelinating Disease
por: Thompson, Kaitlyn K., et al.
Publicado: (2018)

Teriflunomide Promotes Oligodendroglial 8,9-Unsaturated Sterol Accumulation and CNS Remyelination
por: Martin, Elodie, et al.
Publicado: (2021)

Inhibition of phosphodiesterase-4 promotes oligodendrocyte precursor cell differentiation and enhances CNS remyelination
por: Syed, Yasir A, et al.
Publicado: (2013)

Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination
por: Syed, Yasir A., et al.
Publicado: (2015)

Contribution of Schwann Cells to Remyelination in a Naturally Occurring Canine Model of CNS Neuroinflammation
por: Kegler, Kristel, et al.
Publicado: (2015)

Erratum to: Antibody-mediated neutralization of myelin-associated EphrinB3 accelerates CNS remyelination
por: Syed, Yasir A., et al.
Publicado: (2016)

Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination
por: de la Vega Gallardo, Nira, et al.
Publicado: (2020)

Csf1 Deficiency Dysregulates Glial Responses to Demyelination and Disturbs CNS White Matter Remyelination
por: Wylot, Bartosz, et al.
Publicado: (2019)

Gab1 mediates PDGF signaling and is essential to oligodendrocyte differentiation and CNS myelination
por: Zhou, Liang, et al.
Publicado: (2020)

Promoting remyelination in multiple sclerosis
por: Cunniffe, Nick, et al.
Publicado: (2019)

S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS
por: Du, Junqing, et al.
Publicado: (2021)

The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS
por: Chung, S-H, et al.
Publicado: (2015)

IL4I1 augments CNS remyelination and axonal protection by modulating T cell driven inflammation
por: Psachoulia, Konstantina, et al.
Publicado: (2016)

Differential exon expression in myelin basic protein transcripts during central nervous system (CNS) remyelination
por: Jordan, Craig A., et al.
Publicado: (1990)

The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination
por: McMurran, Christopher E., et al.
Publicado: (2019)

PKC modulator bryostatin-1 therapeutically targets CNS innate immunity to attenuate neuroinflammation and promote remyelination
por: Gharibani, Payam, et al.
Publicado: (2023)

Monitoring recovery after CNS demyelination, a novel tool to de-risk pro-remyelinating strategies
por: Henriet, Esther, et al.
Publicado: (2023)

Palmitoylation of Hedgehog proteins by Hedgehog acyltransferase: roles in signalling and disease
por: Resh, Marilyn D.
Publicado: (2021)

Role of canonical Hedgehog signaling pathway in liver
por: Gao, Lili, et al.
Publicado: (2018)

Remyelination as Neuroprotection
por: Howe, Charles L., et al.
Publicado: (2005)

Repair of the Peripheral Nerve—Remyelination that Works
por: Fex Svennigsen, Åsa, et al.
Publicado: (2013)

Remyelination and ageing: Reversing the ravages of time
por: Neumann, Bjoern, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8heo7qecigchg7ngaecrqnql1n