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Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography

Positron emission tomography/computed tomography (PET/CT) plays a vital role in diagnosing tumors. However, PET/CT imaging relies primarily on manual interpretation and labeling by medical professionals. An enormous workload will affect the training samples’ construction for deep learning. The label...

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Autores principales: Ye, Shiping, Chen, Chaoxiang, Bai, Zhican, Wang, Jinming, Yao, Xiaoxaio, Nedzvedz, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320307/
https://www.ncbi.nlm.nih.gov/pubmed/35890851
http://dx.doi.org/10.3390/s22145171
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author Ye, Shiping
Chen, Chaoxiang
Bai, Zhican
Wang, Jinming
Yao, Xiaoxaio
Nedzvedz, Olga
author_facet Ye, Shiping
Chen, Chaoxiang
Bai, Zhican
Wang, Jinming
Yao, Xiaoxaio
Nedzvedz, Olga
author_sort Ye, Shiping
collection PubMed
description Positron emission tomography/computed tomography (PET/CT) plays a vital role in diagnosing tumors. However, PET/CT imaging relies primarily on manual interpretation and labeling by medical professionals. An enormous workload will affect the training samples’ construction for deep learning. The labeling of tumor lesions in PET/CT images involves the intersection of computer graphics and medicine, such as registration, a fusion of medical images, and labeling of lesions. This paper extends the linear interpolation, enhances it in a specific area of the PET image, and uses the outer frame scaling of the PET/CT image and the least-squares residual affine method. The PET and CT images are subjected to wavelet transformation and then synthesized in proportion to form a PET/CT fusion image. According to the absorption of 18F-FDG (fluoro deoxy glucose) SUV in the PET image, the professionals randomly select a point in the focus area in the fusion image, and the system will automatically select the seed point of the focus area to delineate the tumor focus with the regional growth method. Finally, the focus delineated on the PET and CT fusion images is automatically mapped to CT images in the form of polygons, and rectangular segmentation and labeling are formed. This study took the actual PET/CT of patients with lymphatic cancer as an example. The semiautomatic labeling of the system and the manual labeling of imaging specialists were compared and verified. The recognition rate was 93.35%, and the misjudgment rate was 6.52%.
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spelling pubmed-93203072022-07-27 Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography Ye, Shiping Chen, Chaoxiang Bai, Zhican Wang, Jinming Yao, Xiaoxaio Nedzvedz, Olga Sensors (Basel) Article Positron emission tomography/computed tomography (PET/CT) plays a vital role in diagnosing tumors. However, PET/CT imaging relies primarily on manual interpretation and labeling by medical professionals. An enormous workload will affect the training samples’ construction for deep learning. The labeling of tumor lesions in PET/CT images involves the intersection of computer graphics and medicine, such as registration, a fusion of medical images, and labeling of lesions. This paper extends the linear interpolation, enhances it in a specific area of the PET image, and uses the outer frame scaling of the PET/CT image and the least-squares residual affine method. The PET and CT images are subjected to wavelet transformation and then synthesized in proportion to form a PET/CT fusion image. According to the absorption of 18F-FDG (fluoro deoxy glucose) SUV in the PET image, the professionals randomly select a point in the focus area in the fusion image, and the system will automatically select the seed point of the focus area to delineate the tumor focus with the regional growth method. Finally, the focus delineated on the PET and CT fusion images is automatically mapped to CT images in the form of polygons, and rectangular segmentation and labeling are formed. This study took the actual PET/CT of patients with lymphatic cancer as an example. The semiautomatic labeling of the system and the manual labeling of imaging specialists were compared and verified. The recognition rate was 93.35%, and the misjudgment rate was 6.52%. MDPI 2022-07-10 /pmc/articles/PMC9320307/ /pubmed/35890851 http://dx.doi.org/10.3390/s22145171 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Ye, Shiping
Chen, Chaoxiang
Bai, Zhican
Wang, Jinming
Yao, Xiaoxaio
Nedzvedz, Olga
Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography
title Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography
title_full Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography
title_fullStr Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography
title_full_unstemmed Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography
title_short Intelligent Labeling of Tumor Lesions Based on Positron Emission Tomography/Computed Tomography
title_sort intelligent labeling of tumor lesions based on positron emission tomography/computed tomography
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320307/
https://www.ncbi.nlm.nih.gov/pubmed/35890851
http://dx.doi.org/10.3390/s22145171
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