Treatment of Mouse Sperm with a Non-Catalytic Mutant of PLA2G10 Reveals That PLA2G10 Improves In Vitro Fertilization through Both Its Enzymatic Activity and as Ligand of PLA2R1

The group X secreted phospholipase A2 (PLA2G10) is present at high levels in mouse sperm acrosome. The enzyme is secreted during capacitation and amplifies the acrosome reaction and its own secretion via an autocrine loop. PLA2G10 also improves the rate of fertilization. In in vitro fertilization (I...

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Detalles Bibliográficos
Autores principales: Abi Nahed, Roland, Dhellemmes, Magali, Payré, Christine, Le Blévec, Emilie, Perrier, Jean-Philippe, Hennebicq, Sylviane, Escoffier, Jessica, Ray, Pierre F., Loeuillet, Corinne, Lambeau, Gérard, Arnoult, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320362/
https://www.ncbi.nlm.nih.gov/pubmed/35887380
http://dx.doi.org/10.3390/ijms23148033

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