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Novel ABC Transporter Associated with Fluconazole Resistance in Aging of Cryptococcus neoformans

Cryptococcus neoformans causes meningoencephalitis in immunocompromised individuals, which is treated with fluconazole (FLC) monotherapy when resources are limited. This can lead to azole resistance, which can be mediated by overexpression of ABC transporters, a class of efflux pumps. ABC pump-media...

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Detalles Bibliográficos
Autores principales: Oliveira, Natalia Kronbauer, Bhattacharya, Somanon, Gambhir, Rina, Joshi, Manav, Fries, Bettina C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320417/
https://www.ncbi.nlm.nih.gov/pubmed/35887434
http://dx.doi.org/10.3390/jof8070677