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Omeprazole Prevents Colistin-Induced Nephrotoxicity in Rats: Emphasis on Oxidative Stress, Inflammation, Apoptosis and Colistin Accumulation in Kidneys

The clinical value of colistin, a polymyxin antibiotic, is limited by its nephrotoxicity. Omeprazole is a commonly prescribed proton pump inhibitor. The current study aimed to evaluate the effects of the concomitant administration of omeprazole on colistin-induced nephrotoxicity in rats. Omeprazole...

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Detalles Bibliográficos
Autores principales: Nasrullah, Mohammed Z., Eljaaly, Khalid, Neamatallah, Thikryat, Fahmy, Usama A., Alamoudi, Abdulmohsin J., Bakhsh, Hussain T., Abdel-Naim, Ashraf B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320444/
https://www.ncbi.nlm.nih.gov/pubmed/35890080
http://dx.doi.org/10.3390/ph15070782