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Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report

We report the case of a 59-year-old man with squamous cell carcinoma (SCC) of the right mandibular gingiva, who presented with bilateral cervical lymphadenopathy (CLA) after mRNA coronavirus disease 2019 (COVID-19) vaccination. The patient was diagnosed. Imaging studies performed prior to surgery re...

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Autores principales: Kang, Eun-Sung, Kim, Moon-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320456/
https://www.ncbi.nlm.nih.gov/pubmed/35885424
http://dx.doi.org/10.3390/diagnostics12071518
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author Kang, Eun-Sung
Kim, Moon-Young
author_facet Kang, Eun-Sung
Kim, Moon-Young
author_sort Kang, Eun-Sung
collection PubMed
description We report the case of a 59-year-old man with squamous cell carcinoma (SCC) of the right mandibular gingiva, who presented with bilateral cervical lymphadenopathy (CLA) after mRNA coronavirus disease 2019 (COVID-19) vaccination. The patient was diagnosed. Imaging studies performed prior to surgery revealed bilateral CLA and axillary lymphadenopathy (LA) ipsilateral to the vaccination site. Fine-needle aspiration (FNA) biopsy of the left CLA revealed reactive lymph nodes. The patient underwent surgical intervention for the malignant tumor, and the specimen was sent for histopathologic evaluation. The biopsy-proven cancer stage was pT3N0Mx. Positron emission tomography (PET-CT), performed six months after surgery, showed persistent bilateral CLA. However, FNA of the left axillary LA once again showed no evidence of metastasis or recurrence. Since the treatment plan may change based on the type of LA, it is important to figure out whether an mRNA vaccine has been administered to patients with head and neck cancer.
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spelling pubmed-93204562022-07-27 Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report Kang, Eun-Sung Kim, Moon-Young Diagnostics (Basel) Case Report We report the case of a 59-year-old man with squamous cell carcinoma (SCC) of the right mandibular gingiva, who presented with bilateral cervical lymphadenopathy (CLA) after mRNA coronavirus disease 2019 (COVID-19) vaccination. The patient was diagnosed. Imaging studies performed prior to surgery revealed bilateral CLA and axillary lymphadenopathy (LA) ipsilateral to the vaccination site. Fine-needle aspiration (FNA) biopsy of the left CLA revealed reactive lymph nodes. The patient underwent surgical intervention for the malignant tumor, and the specimen was sent for histopathologic evaluation. The biopsy-proven cancer stage was pT3N0Mx. Positron emission tomography (PET-CT), performed six months after surgery, showed persistent bilateral CLA. However, FNA of the left axillary LA once again showed no evidence of metastasis or recurrence. Since the treatment plan may change based on the type of LA, it is important to figure out whether an mRNA vaccine has been administered to patients with head and neck cancer. MDPI 2022-06-21 /pmc/articles/PMC9320456/ /pubmed/35885424 http://dx.doi.org/10.3390/diagnostics12071518 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Kang, Eun-Sung
Kim, Moon-Young
Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report
title Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report
title_full Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report
title_fullStr Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report
title_full_unstemmed Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report
title_short Bilateral Cervical Lymphadenopathy after mRNA COVID-19 Vaccination on Oral Squamous Cell Carcinoma Patient: A Case Report
title_sort bilateral cervical lymphadenopathy after mrna covid-19 vaccination on oral squamous cell carcinoma patient: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320456/
https://www.ncbi.nlm.nih.gov/pubmed/35885424
http://dx.doi.org/10.3390/diagnostics12071518
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