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Analyzing siRNA Concentration, Complexation and Stability in Cationic Dendriplexes by Stem-Loop Reverse Transcription-qPCR

RNA interference (RNAi) is a powerful therapeutic approach for messenger RNA (mRNA) level regulation in human cells. RNAi can be triggered by small interfering RNAs (siRNAs) which are delivered by non-viral carriers, e.g., dendriplexes. siRNA quantification inside carriers is essential in drug deliv...

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Detalles Bibliográficos
Autores principales:	Neugebauer, Maximilian, Grundmann, Clara E., Lehnert, Michael, von Stetten, Felix, Früh, Susanna M., Süss, Regine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320460/ https://www.ncbi.nlm.nih.gov/pubmed/35890243 http://dx.doi.org/10.3390/pharmaceutics14071348

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