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Vascular Repair by Grafting Based on Magnetic Nanoparticles
Magnetic nanoparticles (MNPs) have attracted much attention in the past few decades because of their unique magnetic responsiveness. Especially in the diagnosis and treatment of diseases, they are mostly involved in non-invasive ways and have achieved good results. The magnetic responsiveness of MNP...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320478/ https://www.ncbi.nlm.nih.gov/pubmed/35890328 http://dx.doi.org/10.3390/pharmaceutics14071433 |
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author | Liu, Xin Wang, Nan Liu, Xiyu Deng, Rongrong Kang, Ran Xie, Lin |
author_facet | Liu, Xin Wang, Nan Liu, Xiyu Deng, Rongrong Kang, Ran Xie, Lin |
author_sort | Liu, Xin |
collection | PubMed |
description | Magnetic nanoparticles (MNPs) have attracted much attention in the past few decades because of their unique magnetic responsiveness. Especially in the diagnosis and treatment of diseases, they are mostly involved in non-invasive ways and have achieved good results. The magnetic responsiveness of MNPs is strictly controlled by the size, crystallinity, uniformity, and surface properties of the synthesized particles. In this review, we summarized the classification of MNPs and their application in vascular repair. MNPs mainly use their unique magnetic properties to participate in vascular repair, including magnetic stimulation, magnetic drive, magnetic resonance imaging, magnetic hyperthermia, magnetic assembly scaffolds, and magnetic targeted drug delivery, which can significantly affect scaffold performance, cell behavior, factor secretion, drug release, etc. Although there are still challenges in the large-scale clinical application of MNPs, its good non-invasive way to participate in vascular repair and the establishment of a continuous detection process is still the future development direction. |
format | Online Article Text |
id | pubmed-9320478 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93204782022-07-27 Vascular Repair by Grafting Based on Magnetic Nanoparticles Liu, Xin Wang, Nan Liu, Xiyu Deng, Rongrong Kang, Ran Xie, Lin Pharmaceutics Review Magnetic nanoparticles (MNPs) have attracted much attention in the past few decades because of their unique magnetic responsiveness. Especially in the diagnosis and treatment of diseases, they are mostly involved in non-invasive ways and have achieved good results. The magnetic responsiveness of MNPs is strictly controlled by the size, crystallinity, uniformity, and surface properties of the synthesized particles. In this review, we summarized the classification of MNPs and their application in vascular repair. MNPs mainly use their unique magnetic properties to participate in vascular repair, including magnetic stimulation, magnetic drive, magnetic resonance imaging, magnetic hyperthermia, magnetic assembly scaffolds, and magnetic targeted drug delivery, which can significantly affect scaffold performance, cell behavior, factor secretion, drug release, etc. Although there are still challenges in the large-scale clinical application of MNPs, its good non-invasive way to participate in vascular repair and the establishment of a continuous detection process is still the future development direction. MDPI 2022-07-08 /pmc/articles/PMC9320478/ /pubmed/35890328 http://dx.doi.org/10.3390/pharmaceutics14071433 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Liu, Xin Wang, Nan Liu, Xiyu Deng, Rongrong Kang, Ran Xie, Lin Vascular Repair by Grafting Based on Magnetic Nanoparticles |
title | Vascular Repair by Grafting Based on Magnetic Nanoparticles |
title_full | Vascular Repair by Grafting Based on Magnetic Nanoparticles |
title_fullStr | Vascular Repair by Grafting Based on Magnetic Nanoparticles |
title_full_unstemmed | Vascular Repair by Grafting Based on Magnetic Nanoparticles |
title_short | Vascular Repair by Grafting Based on Magnetic Nanoparticles |
title_sort | vascular repair by grafting based on magnetic nanoparticles |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320478/ https://www.ncbi.nlm.nih.gov/pubmed/35890328 http://dx.doi.org/10.3390/pharmaceutics14071433 |
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