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Vascular Repair by Grafting Based on Magnetic Nanoparticles

Magnetic nanoparticles (MNPs) have attracted much attention in the past few decades because of their unique magnetic responsiveness. Especially in the diagnosis and treatment of diseases, they are mostly involved in non-invasive ways and have achieved good results. The magnetic responsiveness of MNP...

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Detalles Bibliográficos
Autores principales: Liu, Xin, Wang, Nan, Liu, Xiyu, Deng, Rongrong, Kang, Ran, Xie, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320478/
https://www.ncbi.nlm.nih.gov/pubmed/35890328
http://dx.doi.org/10.3390/pharmaceutics14071433
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author Liu, Xin
Wang, Nan
Liu, Xiyu
Deng, Rongrong
Kang, Ran
Xie, Lin
author_facet Liu, Xin
Wang, Nan
Liu, Xiyu
Deng, Rongrong
Kang, Ran
Xie, Lin
author_sort Liu, Xin
collection PubMed
description Magnetic nanoparticles (MNPs) have attracted much attention in the past few decades because of their unique magnetic responsiveness. Especially in the diagnosis and treatment of diseases, they are mostly involved in non-invasive ways and have achieved good results. The magnetic responsiveness of MNPs is strictly controlled by the size, crystallinity, uniformity, and surface properties of the synthesized particles. In this review, we summarized the classification of MNPs and their application in vascular repair. MNPs mainly use their unique magnetic properties to participate in vascular repair, including magnetic stimulation, magnetic drive, magnetic resonance imaging, magnetic hyperthermia, magnetic assembly scaffolds, and magnetic targeted drug delivery, which can significantly affect scaffold performance, cell behavior, factor secretion, drug release, etc. Although there are still challenges in the large-scale clinical application of MNPs, its good non-invasive way to participate in vascular repair and the establishment of a continuous detection process is still the future development direction.
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spelling pubmed-93204782022-07-27 Vascular Repair by Grafting Based on Magnetic Nanoparticles Liu, Xin Wang, Nan Liu, Xiyu Deng, Rongrong Kang, Ran Xie, Lin Pharmaceutics Review Magnetic nanoparticles (MNPs) have attracted much attention in the past few decades because of their unique magnetic responsiveness. Especially in the diagnosis and treatment of diseases, they are mostly involved in non-invasive ways and have achieved good results. The magnetic responsiveness of MNPs is strictly controlled by the size, crystallinity, uniformity, and surface properties of the synthesized particles. In this review, we summarized the classification of MNPs and their application in vascular repair. MNPs mainly use their unique magnetic properties to participate in vascular repair, including magnetic stimulation, magnetic drive, magnetic resonance imaging, magnetic hyperthermia, magnetic assembly scaffolds, and magnetic targeted drug delivery, which can significantly affect scaffold performance, cell behavior, factor secretion, drug release, etc. Although there are still challenges in the large-scale clinical application of MNPs, its good non-invasive way to participate in vascular repair and the establishment of a continuous detection process is still the future development direction. MDPI 2022-07-08 /pmc/articles/PMC9320478/ /pubmed/35890328 http://dx.doi.org/10.3390/pharmaceutics14071433 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Liu, Xin
Wang, Nan
Liu, Xiyu
Deng, Rongrong
Kang, Ran
Xie, Lin
Vascular Repair by Grafting Based on Magnetic Nanoparticles
title Vascular Repair by Grafting Based on Magnetic Nanoparticles
title_full Vascular Repair by Grafting Based on Magnetic Nanoparticles
title_fullStr Vascular Repair by Grafting Based on Magnetic Nanoparticles
title_full_unstemmed Vascular Repair by Grafting Based on Magnetic Nanoparticles
title_short Vascular Repair by Grafting Based on Magnetic Nanoparticles
title_sort vascular repair by grafting based on magnetic nanoparticles
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320478/
https://www.ncbi.nlm.nih.gov/pubmed/35890328
http://dx.doi.org/10.3390/pharmaceutics14071433
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