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PPARβ/δ Augments IL-1β-Induced COX-2 Expression and PGE2 Biosynthesis in Human Mesangial Cells via the Activation of SIRT1

Peroxisome proliferator-activated receptor β/δ (PPARβ/δ), a ligand-activated nuclear receptor, regulates lipid and glucose metabolism and inflammation. PPARβ/δ can exert an anti-inflammatory effect by suppressing proinflammatory cytokine production. Cyclooxygenase-2 (COX-2)-triggered inflammation pl...

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Detalles Bibliográficos
Autores principales:	Li, Yaqing, Cao, Rong, Gu, Tingting, Cao, Cong, Chen, Tingyue, Guan, Youfei, Zhang, Xiaoyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320509/ https://www.ncbi.nlm.nih.gov/pubmed/35888719 http://dx.doi.org/10.3390/metabo12070595

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