E3 ubiquitin ligase RBX1 drives the metastasis of triple negative breast cancer through a FBXO45-TWIST1-dependent degradation mechanism

Triple-negative breast cancer (TNBC) patients are at high risk of recurrence and metastasis in the early stages, although receiving standard treatment. However, the underlying mechanism of TNBC remains unclear. Here, the critical effect of E3 ubiquitin ligase RBX1 in the metastasis of TNBC was repor...

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Detalles Bibliográficos
Autores principales: Shao, Jun, Feng, Qian, Jiang, Weifan, Yang, Yuting, Liu, Zhiqiang, Li, Liang, Yang, Wenlong, Zou, Yufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320552/
https://www.ncbi.nlm.nih.gov/pubmed/35802537
http://dx.doi.org/10.18632/aging.204163

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