Targeted Therapy of HPV Positive and Negative Tonsillar Squamous Cell Carcinoma Cell Lines Reveals Synergy between CDK4/6, PI3K and Sometimes FGFR Inhibitors, but Rarely between PARP and WEE1 Inhibitors

Human papillomavirus positive (HPV(+)) tonsillar and base of tongue squamous cell carcinoma (TSCC/BOTSCC) have a favorable outcome, but upon relapse, survival is poor and new therapeutical options are needed. Recently, we found synergistic effects by combining the food and drug administration approv...

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Detalles Bibliográficos
Autores principales: Kostopoulou, Ourania N., Zupancic, Mark, Pont, Mariona, Papin, Emma, Lukoseviciute, Monika, Mikelarena, Borja Agirre, Holzhauser, Stefan, Dalianis, Tina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320646/
https://www.ncbi.nlm.nih.gov/pubmed/35891353
http://dx.doi.org/10.3390/v14071372

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