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TP53-Status-Dependent Oncogenic EZH2 Activity in Pancreatic Cancer

SIMPLE SUMMARY: Epigenetic alterations contribute to the aggressiveness and therapy resistance of Pancreatic Ductal Adenocarcinoma (PDAC). However, epigenetic regulators, including Enhancer of Zeste Homolog 2 (EZH2), reveal a strong context-dependent activity. Our study aimed to examine the context-...

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Detalles Bibliográficos
Autores principales: Versemann, Lennart, Patil, Shilpa, Steuber, Benjamin, Zhang, Zhe, Kopp, Waltraut, Krawczyk, Hannah Elisa, Kaulfuß, Silke, Wollnik, Bernd, Ströbel, Philipp, Neesse, Albrecht, Singh, Shiv K., Ellenrieder, Volker, Hessmann, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320674/
https://www.ncbi.nlm.nih.gov/pubmed/35884510
http://dx.doi.org/10.3390/cancers14143451