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The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia
This is a retrospective study investigating the relationship between ultrasound and magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is a rare cause of pulmonary hypoplasia that increases the mortality and morbidity of patients. Inclusion criteria were: pat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320675/ https://www.ncbi.nlm.nih.gov/pubmed/35885637 http://dx.doi.org/10.3390/diagnostics12071733 |
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author | Neștianu, Erick George Brădeanu, Cristina Guramba Alexandru, Dragoș Ovidiu Vlădăreanu, Radu |
author_facet | Neștianu, Erick George Brădeanu, Cristina Guramba Alexandru, Dragoș Ovidiu Vlădăreanu, Radu |
author_sort | Neștianu, Erick George |
collection | PubMed |
description | This is a retrospective study investigating the relationship between ultrasound and magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is a rare cause of pulmonary hypoplasia that increases the mortality and morbidity of patients. Inclusion criteria were: patients diagnosed with CDH who underwent MRI examination after the second-trimester morphology ultrasound confirmed the presence of CDH. The patients came from three university hospitals in Bucharest, Romania. A total of 22 patients were included in the study after applying the exclusion criteria. By analyzing the total lung volume (TLV) using MRI, and the lung to head ratio (LHR) calculated using MRI and ultrasound, we observed that LHR can severely underestimate the severity of the pulmonary hypoplasia, even showing values close to normal in some cases. This also proves to be statistically relevant if we eliminate certain extreme values. We found significant correlations between the LHR percentage and herniated organs, such as the left and right liver lobes and gallbladder. MRI also provided additional insights, indicating the presence of pericarditis or pleurisy. We wish to underline the necessity of MRI follow-up in all cases of CDH, as the accurate measurement of the TLV is important for future treatment and therapeutic strategy. |
format | Online Article Text |
id | pubmed-9320675 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93206752022-07-27 The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia Neștianu, Erick George Brădeanu, Cristina Guramba Alexandru, Dragoș Ovidiu Vlădăreanu, Radu Diagnostics (Basel) Article This is a retrospective study investigating the relationship between ultrasound and magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is a rare cause of pulmonary hypoplasia that increases the mortality and morbidity of patients. Inclusion criteria were: patients diagnosed with CDH who underwent MRI examination after the second-trimester morphology ultrasound confirmed the presence of CDH. The patients came from three university hospitals in Bucharest, Romania. A total of 22 patients were included in the study after applying the exclusion criteria. By analyzing the total lung volume (TLV) using MRI, and the lung to head ratio (LHR) calculated using MRI and ultrasound, we observed that LHR can severely underestimate the severity of the pulmonary hypoplasia, even showing values close to normal in some cases. This also proves to be statistically relevant if we eliminate certain extreme values. We found significant correlations between the LHR percentage and herniated organs, such as the left and right liver lobes and gallbladder. MRI also provided additional insights, indicating the presence of pericarditis or pleurisy. We wish to underline the necessity of MRI follow-up in all cases of CDH, as the accurate measurement of the TLV is important for future treatment and therapeutic strategy. MDPI 2022-07-17 /pmc/articles/PMC9320675/ /pubmed/35885637 http://dx.doi.org/10.3390/diagnostics12071733 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Neștianu, Erick George Brădeanu, Cristina Guramba Alexandru, Dragoș Ovidiu Vlădăreanu, Radu The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia |
title | The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia |
title_full | The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia |
title_fullStr | The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia |
title_full_unstemmed | The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia |
title_short | The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia |
title_sort | necessity of magnetic resonance imaging in congenital diaphragmatic hernia |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320675/ https://www.ncbi.nlm.nih.gov/pubmed/35885637 http://dx.doi.org/10.3390/diagnostics12071733 |
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