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The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia

This is a retrospective study investigating the relationship between ultrasound and magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is a rare cause of pulmonary hypoplasia that increases the mortality and morbidity of patients. Inclusion criteria were: pat...

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Autores principales: Neștianu, Erick George, Brădeanu, Cristina Guramba, Alexandru, Dragoș Ovidiu, Vlădăreanu, Radu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320675/
https://www.ncbi.nlm.nih.gov/pubmed/35885637
http://dx.doi.org/10.3390/diagnostics12071733
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author Neștianu, Erick George
Brădeanu, Cristina Guramba
Alexandru, Dragoș Ovidiu
Vlădăreanu, Radu
author_facet Neștianu, Erick George
Brădeanu, Cristina Guramba
Alexandru, Dragoș Ovidiu
Vlădăreanu, Radu
author_sort Neștianu, Erick George
collection PubMed
description This is a retrospective study investigating the relationship between ultrasound and magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is a rare cause of pulmonary hypoplasia that increases the mortality and morbidity of patients. Inclusion criteria were: patients diagnosed with CDH who underwent MRI examination after the second-trimester morphology ultrasound confirmed the presence of CDH. The patients came from three university hospitals in Bucharest, Romania. A total of 22 patients were included in the study after applying the exclusion criteria. By analyzing the total lung volume (TLV) using MRI, and the lung to head ratio (LHR) calculated using MRI and ultrasound, we observed that LHR can severely underestimate the severity of the pulmonary hypoplasia, even showing values close to normal in some cases. This also proves to be statistically relevant if we eliminate certain extreme values. We found significant correlations between the LHR percentage and herniated organs, such as the left and right liver lobes and gallbladder. MRI also provided additional insights, indicating the presence of pericarditis or pleurisy. We wish to underline the necessity of MRI follow-up in all cases of CDH, as the accurate measurement of the TLV is important for future treatment and therapeutic strategy.
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spelling pubmed-93206752022-07-27 The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia Neștianu, Erick George Brădeanu, Cristina Guramba Alexandru, Dragoș Ovidiu Vlădăreanu, Radu Diagnostics (Basel) Article This is a retrospective study investigating the relationship between ultrasound and magnetic resonance imaging (MRI) examinations in congenital diaphragmatic hernia (CDH). CDH is a rare cause of pulmonary hypoplasia that increases the mortality and morbidity of patients. Inclusion criteria were: patients diagnosed with CDH who underwent MRI examination after the second-trimester morphology ultrasound confirmed the presence of CDH. The patients came from three university hospitals in Bucharest, Romania. A total of 22 patients were included in the study after applying the exclusion criteria. By analyzing the total lung volume (TLV) using MRI, and the lung to head ratio (LHR) calculated using MRI and ultrasound, we observed that LHR can severely underestimate the severity of the pulmonary hypoplasia, even showing values close to normal in some cases. This also proves to be statistically relevant if we eliminate certain extreme values. We found significant correlations between the LHR percentage and herniated organs, such as the left and right liver lobes and gallbladder. MRI also provided additional insights, indicating the presence of pericarditis or pleurisy. We wish to underline the necessity of MRI follow-up in all cases of CDH, as the accurate measurement of the TLV is important for future treatment and therapeutic strategy. MDPI 2022-07-17 /pmc/articles/PMC9320675/ /pubmed/35885637 http://dx.doi.org/10.3390/diagnostics12071733 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Neștianu, Erick George
Brădeanu, Cristina Guramba
Alexandru, Dragoș Ovidiu
Vlădăreanu, Radu
The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia
title The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia
title_full The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia
title_fullStr The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia
title_full_unstemmed The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia
title_short The Necessity of Magnetic Resonance Imaging in Congenital Diaphragmatic Hernia
title_sort necessity of magnetic resonance imaging in congenital diaphragmatic hernia
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320675/
https://www.ncbi.nlm.nih.gov/pubmed/35885637
http://dx.doi.org/10.3390/diagnostics12071733
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