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Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City

The emergence of the Omicron variant was accompanied by an acute increase in COVID-19 cases and hospitalizations in New York City. An increased incidence of COVID-19-associated croup in children during the Omicron wave has been recognized, suggesting that there may be other changes in clinical sympt...

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Autores principales: Acker, Karen P., Levine, Deborah A., Varghese, Mathew, Nash, Katherine A., RoyChoudhury, Arindam, Abramson, Erika L., Grinspan, Zachary M., Simmons, Will, Wu, Alan, Han, Jin-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320728/
https://www.ncbi.nlm.nih.gov/pubmed/35884027
http://dx.doi.org/10.3390/children9071043
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author Acker, Karen P.
Levine, Deborah A.
Varghese, Mathew
Nash, Katherine A.
RoyChoudhury, Arindam
Abramson, Erika L.
Grinspan, Zachary M.
Simmons, Will
Wu, Alan
Han, Jin-Young
author_facet Acker, Karen P.
Levine, Deborah A.
Varghese, Mathew
Nash, Katherine A.
RoyChoudhury, Arindam
Abramson, Erika L.
Grinspan, Zachary M.
Simmons, Will
Wu, Alan
Han, Jin-Young
author_sort Acker, Karen P.
collection PubMed
description The emergence of the Omicron variant was accompanied by an acute increase in COVID-19 cases and hospitalizations in New York City. An increased incidence of COVID-19-associated croup in children during the Omicron wave has been recognized, suggesting that there may be other changes in clinical symptoms and severity. To better understand clinical outcomes and health care utilization in children infected with SARS-CoV-2 during the Omicron wave, we performed a cross-sectional study in pediatric patients aged ≤18 years who were tested for SARS-CoV-2 in pediatric emergency departments within a large medical system in New York City from 2 December 2021 to 23 January 2022. We described the clinical characteristics and outcomes of pediatric patients who presented to the pediatric emergency department and were hospitalized with SARS-CoV-2 infection during the Omicron wave in New York City. There were 2515 children tested in the ED for SARS-CoV-2 of whom 794 (31.6%) tested positive. Fifty-eight children were hospitalized for a COVID-19-related indication, representing 7.3% of all COVID-19-positive children and 72% of hospitalized COVID-19-positive children. Most (64%) children hospitalized for a COVID-19-related indication were less than 5 years old. Indications for hospitalization included respiratory symptoms, clinical monitoring of patients with comorbid conditions, and exacerbations of underlying disease. Eleven (19%) hospitalized children were admitted to the ICU and six (10%) required mechanical ventilation. Children infected with COVID-19 during the Omicron wave, particularly those less than 5 years old, were at risk for hospitalization. A majority of hospitalizations were directly related to COVID-19 infection although clinical indications varied with less than a half being admitted for respiratory diseases including croup. Our findings underscore the need for an effective COVID-19 vaccine in those less than 5 years old, continued monitoring for changes in clinical outcomes and health care utilization in children as more SARS-CoV-2 variants emerge, and understanding that children are often admitted for non-respiratory diseases with COVID-19.
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spelling pubmed-93207282022-07-27 Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City Acker, Karen P. Levine, Deborah A. Varghese, Mathew Nash, Katherine A. RoyChoudhury, Arindam Abramson, Erika L. Grinspan, Zachary M. Simmons, Will Wu, Alan Han, Jin-Young Children (Basel) Article The emergence of the Omicron variant was accompanied by an acute increase in COVID-19 cases and hospitalizations in New York City. An increased incidence of COVID-19-associated croup in children during the Omicron wave has been recognized, suggesting that there may be other changes in clinical symptoms and severity. To better understand clinical outcomes and health care utilization in children infected with SARS-CoV-2 during the Omicron wave, we performed a cross-sectional study in pediatric patients aged ≤18 years who were tested for SARS-CoV-2 in pediatric emergency departments within a large medical system in New York City from 2 December 2021 to 23 January 2022. We described the clinical characteristics and outcomes of pediatric patients who presented to the pediatric emergency department and were hospitalized with SARS-CoV-2 infection during the Omicron wave in New York City. There were 2515 children tested in the ED for SARS-CoV-2 of whom 794 (31.6%) tested positive. Fifty-eight children were hospitalized for a COVID-19-related indication, representing 7.3% of all COVID-19-positive children and 72% of hospitalized COVID-19-positive children. Most (64%) children hospitalized for a COVID-19-related indication were less than 5 years old. Indications for hospitalization included respiratory symptoms, clinical monitoring of patients with comorbid conditions, and exacerbations of underlying disease. Eleven (19%) hospitalized children were admitted to the ICU and six (10%) required mechanical ventilation. Children infected with COVID-19 during the Omicron wave, particularly those less than 5 years old, were at risk for hospitalization. A majority of hospitalizations were directly related to COVID-19 infection although clinical indications varied with less than a half being admitted for respiratory diseases including croup. Our findings underscore the need for an effective COVID-19 vaccine in those less than 5 years old, continued monitoring for changes in clinical outcomes and health care utilization in children as more SARS-CoV-2 variants emerge, and understanding that children are often admitted for non-respiratory diseases with COVID-19. MDPI 2022-07-14 /pmc/articles/PMC9320728/ /pubmed/35884027 http://dx.doi.org/10.3390/children9071043 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Acker, Karen P.
Levine, Deborah A.
Varghese, Mathew
Nash, Katherine A.
RoyChoudhury, Arindam
Abramson, Erika L.
Grinspan, Zachary M.
Simmons, Will
Wu, Alan
Han, Jin-Young
Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City
title Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City
title_full Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City
title_fullStr Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City
title_full_unstemmed Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City
title_short Indications for Hospitalization in Children with SARS-CoV-2 Infection during the Omicron Wave in New York City
title_sort indications for hospitalization in children with sars-cov-2 infection during the omicron wave in new york city
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320728/
https://www.ncbi.nlm.nih.gov/pubmed/35884027
http://dx.doi.org/10.3390/children9071043
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