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A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables

Micronutrients are required in many reactions involved in physical activity and exercise. Most physically active people do not meet the body’s needs in terms of micronutrients through diet. The novelty of the present manuscript is the use of an innovative dietary approach to supply micronutrients to...

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Autores principales: Baldassano, Sara, Polizzi, Maria Rita, Sabatino, Leo, Caldarella, Rosalia, Macaluso, Andrea, Alongi, Angelina, Caldara, Gaetano Felice, Ferrantelli, Vincenzo, Vasto, Sonya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320783/
https://www.ncbi.nlm.nih.gov/pubmed/35889926
http://dx.doi.org/10.3390/nu14142971
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author Baldassano, Sara
Polizzi, Maria Rita
Sabatino, Leo
Caldarella, Rosalia
Macaluso, Andrea
Alongi, Angelina
Caldara, Gaetano Felice
Ferrantelli, Vincenzo
Vasto, Sonya
author_facet Baldassano, Sara
Polizzi, Maria Rita
Sabatino, Leo
Caldarella, Rosalia
Macaluso, Andrea
Alongi, Angelina
Caldara, Gaetano Felice
Ferrantelli, Vincenzo
Vasto, Sonya
author_sort Baldassano, Sara
collection PubMed
description Micronutrients are required in many reactions involved in physical activity and exercise. Most physically active people do not meet the body’s needs in terms of micronutrients through diet. The novelty of the present manuscript is the use of an innovative dietary approach to supply micronutrients to physically active people through biofortified food. Therefore, the key point of this study was to verify whether supplementation with biofortified vegetables—and specifically molybdenum (Mo)-enriched lettuce—in healthy volunteers affects essential regulators of body homeostasis and, specifically, hematological parameters, iron and lipid metabolism, and hepatic function. Twenty-four healthy volunteers were allocated in a double-blinded manner to either a control group that consumed lettuce, or the intervention group, which consumed Mo-enriched lettuce, for 12 days. Blood samples were collected at baseline (T0) and after 12 days (T1). We found that supplementation with Mo-enriched lettuce did not affect hematological parameters, liver function, or lipid metabolism, but significantly improved iron homeostasis by increasing non-binding hemoglobin iron by about 37% and transferrin saturation by about 42%, while proteins of iron metabolism (e.g., transferrin, ferritin, ceruloplasmin) were not affected. The serum molybdenum concentration increased by about 42%. In conclusion, this study shows that consumption of Mo-biofortified lettuce ameliorates iron homeostasis in healthy subjects, and suggests that it could be used as a new nutritional supplementation strategy to avoid iron deficiency in physically active people.
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spelling pubmed-93207832022-07-27 A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables Baldassano, Sara Polizzi, Maria Rita Sabatino, Leo Caldarella, Rosalia Macaluso, Andrea Alongi, Angelina Caldara, Gaetano Felice Ferrantelli, Vincenzo Vasto, Sonya Nutrients Article Micronutrients are required in many reactions involved in physical activity and exercise. Most physically active people do not meet the body’s needs in terms of micronutrients through diet. The novelty of the present manuscript is the use of an innovative dietary approach to supply micronutrients to physically active people through biofortified food. Therefore, the key point of this study was to verify whether supplementation with biofortified vegetables—and specifically molybdenum (Mo)-enriched lettuce—in healthy volunteers affects essential regulators of body homeostasis and, specifically, hematological parameters, iron and lipid metabolism, and hepatic function. Twenty-four healthy volunteers were allocated in a double-blinded manner to either a control group that consumed lettuce, or the intervention group, which consumed Mo-enriched lettuce, for 12 days. Blood samples were collected at baseline (T0) and after 12 days (T1). We found that supplementation with Mo-enriched lettuce did not affect hematological parameters, liver function, or lipid metabolism, but significantly improved iron homeostasis by increasing non-binding hemoglobin iron by about 37% and transferrin saturation by about 42%, while proteins of iron metabolism (e.g., transferrin, ferritin, ceruloplasmin) were not affected. The serum molybdenum concentration increased by about 42%. In conclusion, this study shows that consumption of Mo-biofortified lettuce ameliorates iron homeostasis in healthy subjects, and suggests that it could be used as a new nutritional supplementation strategy to avoid iron deficiency in physically active people. MDPI 2022-07-20 /pmc/articles/PMC9320783/ /pubmed/35889926 http://dx.doi.org/10.3390/nu14142971 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Baldassano, Sara
Polizzi, Maria Rita
Sabatino, Leo
Caldarella, Rosalia
Macaluso, Andrea
Alongi, Angelina
Caldara, Gaetano Felice
Ferrantelli, Vincenzo
Vasto, Sonya
A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables
title A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables
title_full A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables
title_fullStr A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables
title_full_unstemmed A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables
title_short A New Potential Dietary Approach to Supply Micronutrients to Physically Active People through Consumption of Biofortified Vegetables
title_sort new potential dietary approach to supply micronutrients to physically active people through consumption of biofortified vegetables
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320783/
https://www.ncbi.nlm.nih.gov/pubmed/35889926
http://dx.doi.org/10.3390/nu14142971
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