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Efanesoctocog alfa elicits functional clot formation that is indistinguishable to that of recombinant factor VIII

BACKGROUND: Factor VIII (FVIII) binding to endogenous von Willebrand factor (VWF) has constrained half‐life extension of recombinant FVIII (rFVIII) products for hemophilia A. Efanesoctocog alfa (rFVIIIFc‐VWF‐XTEN; BIVV001) is a novel fusion protein designed to decouple FVIII from VWF in circulation...

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Detalles Bibliográficos
Autores principales:	Demers, Melanie, Aleman, Maria M., Kistanova, Elena, Peters, Robert, Salas, Joe, Seth Chhabra, Ekta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	THROMBOSIS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320793/ https://www.ncbi.nlm.nih.gov/pubmed/35466511 http://dx.doi.org/10.1111/jth.15741

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