Cargando…

S-Adenosylmethionine Inhibits Colorectal Cancer Cell Migration through Mirna-Mediated Targeting of Notch Signaling Pathway †

Metastasis is a leading cause of mortality and poor prognosis in colorectal cancer (CRC). Thus, the identification of new compounds targeting cell migration represents a major clinical challenge. Recent findings evidenced a central role for dysregulated Notch in CRC and a correlation between Notch o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borzacchiello, Luigi, Veglia Tranchese, Roberta, Grillo, Roberta, Arpino, Roberta, Mosca, Laura, Cacciapuoti, Giovanna, Porcelli, Marina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320859/ https://www.ncbi.nlm.nih.gov/pubmed/35887021 http://dx.doi.org/10.3390/ijms23147673

Ejemplares similares

Mutual Correlation between Non-Coding RNA and S-Adenosylmethionine in Human Cancer: Roles and Therapeutic Opportunities
por: Mosca, Laura, et al.
Publicado: (2021)

S-Adenosylmethionine Increases the Sensitivity of Human Colorectal Cancer Cells to 5-Fluorouracil by Inhibiting P-Glycoprotein Expression and NF-κB Activation
por: Mosca, Laura, et al.
Publicado: (2021)

S-Adenosylmethionine Inhibits Cell Growth and Migration of Triple Negative Breast Cancer Cells through Upregulating MiRNA-34c and MiRNA-449a
por: Coppola, Alessandra, et al.
Publicado: (2020)

Therapeutic Potential of the Natural Compound S-Adenosylmethionine as a Chemoprotective Synergistic Agent in Breast, and Head and Neck Cancer Treatment: Current Status of Research
por: Mosca, Laura, et al.
Publicado: (2020)

Mi-RNA-888-5p Is Involved in S-Adenosylmethionine Antitumor Effects in Laryngeal Squamous Cancer Cells
por: Pagano, Martina, et al.
Publicado: (2020)

S-Adenosylmethionine regulates apoptosis and autophagy in MCF-7 breast cancer cells through the modulation of specific microRNAs
por: Ilisso, Concetta Paola, et al.
Publicado: (2018)

S-Adenosyl-l-Methionine Overcomes uL3-Mediated Drug Resistance in p53 Deleted Colon Cancer Cells
por: Mosca, Laura, et al.
Publicado: (2020)

Protective Effect of Tyrosol and S-Adenosylmethionine against Ethanol-Induced Oxidative Stress of Hepg2 Cells Involves Sirtuin 1, P53 and Erk1/2 Signaling
por: Stiuso, Paola, et al.
Publicado: (2016)

Effects of S-adenosyl-L-methionine on the invasion and migration of head and neck squamous cancer cells and analysis of the underlying mechanisms
por: Mosca, Laura, et al.
Publicado: (2020)

Annurca apple polyphenol extract promotes mesenchymal-to-epithelial transition and inhibits migration in triple-negative breast cancer cells through ROS/JNK signaling
por: Vuoso, Daniela Cristina, et al.
Publicado: (2020)

Polyphenol Extract from “Greco” Grape Canes: Characterization, Antioxidant Capacity, and Antitumor Effects on Cal-33 and JHU-SCC-011 Head and Neck Squamous Cell Carcinoma
por: Squillaci, Giuseppe, et al.
Publicado: (2022)

Hepatic levels of S-adenosylmethionine regulate the adaptive response to fasting
por: Capelo-Diz, Alba, et al.
Publicado: (2023)

The Biochemistry of Adenosylmethionine
por: Kraus, Jan
Publicado: (1978)

Annurca apple polyphenol extract selectively kills MDA-MB-231 cells through ROS generation, sustained JNK activation and cell growth and survival inhibition
por: Martino, Elisa, et al.
Publicado: (2019)

Radical S-Adenosylmethionine Enzymes
por: Broderick, Joan B., et al.
Publicado: (2014)

Excess S-adenosylmethionine inhibits methylation via catabolism to adenine
por: Fukumoto, Kazuki, et al.
Publicado: (2022)

Metabolic engineering of Bacillus amyloliquefaciens for enhanced production of S-adenosylmethionine by coupling of an engineered S-adenosylmethionine pathway and the tricarboxylic acid cycle
por: Ruan, Liying, et al.
Publicado: (2019)

Structure and function study of the complex that synthesizes S-adenosylmethionine
por: Murray, Ben, et al.
Publicado: (2014)

Natural history of S-adenosylmethionine-binding proteins
por: Kozbial, Piotr Z, et al.
Publicado: (2005)

Potential role of S-adenosylmethionine in osteosarcoma development
por: Shi, Hui, et al.
Publicado: (2016)

New Insights into the Design of Inhibitors of Human S-Adenosylmethionine Decarboxylase: Studies of Adenine C(8) Substitution in Structural Analogues of S-Adenosylmethionine
por: McCloskey, Diane E., et al.
Publicado: (2009)

Engineered Pichia pastoris for enhanced production of S-adenosylmethionine
por: Kamarthapu, Venu, et al.
Publicado: (2013)

S‐adenosylmethionine: A metabolite critical to the regulation of autophagy
por: Ouyang, Yang, et al.
Publicado: (2020)

Rethinking the bioavailability and cellular transport properties of S-adenosylmethionine
por: Sun, Yudong, et al.
Publicado: (2021)

Sinefungin, a Natural Nucleoside Analogue of S-Adenosylmethionine, Inhibits Streptococcus pneumoniae Biofilm Growth
por: Yadav, Mukesh Kumar, et al.
Publicado: (2014)

Structural basis for the regulation of human 5,10-methylenetetrahydrofolate reductase by phosphorylation and S-adenosylmethionine inhibition
por: Froese, D. Sean, et al.
Publicado: (2018)

S-adenosylmethionine administration inhibits levodopa-induced vascular endothelial growth factor-A expression
por: Yan, Yuanliang, et al.
Publicado: (2020)

S-Adenosylmethionine: From the Discovery of Its Inhibition of Tumorigenesis to Its Use as a Therapeutic Agent
por: Pascale, Rosa M., et al.
Publicado: (2022)

S-Adenosylmethionine Affects Cell Cycle Pathways and Suppresses Proliferation in Liver Cells
por: Yan, Lu, et al.
Publicado: (2019)

MiR-139-5p inhibits migration and invasion of colorectal cancer by downregulating AMFR and NOTCH1
por: Song, Mingxu, et al.
Publicado: (2014)

The miR-1-NOTCH3-Asef Pathway Is Important for Colorectal Tumor Cell Migration
por: Furukawa, Shiori, et al.
Publicado: (2013)

Notch signaling in pediatric soft tissue sarcomas
por: Rota, Rossella, et al.
Publicado: (2012)

S-Adenosylmethionine May Mitigate Obstructive Sleep Apnea in an Adult with Down Syndrome: A Case Report
por: Dragonieri, Silvano, et al.
Publicado: (2022)

An unusual S-adenosylmethionine synthetase gene from dinoflagellate is methylated
por: Ho, Percy, et al.
Publicado: (2007)

Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase
por: Bale, Shridhar, et al.
Publicado: (2008)

Pharmacogenetics of thiopurine therapy: from thiopurine S-methyltransferase to S-adenosylmethionine
por: Mlinarič-Raščan, Irena, et al.
Publicado: (2009)

Paramagnetic Intermediates Generated by Radical S-Adenosylmethionine (SAM) Enzymes
por: Stich, Troy A., et al.
Publicado: (2014)

Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans
por: Elshorbagy, A K, et al.
Publicado: (2016)

Coupling S-adenosylmethionine–dependent methylation to growth: Design and uses
por: Luo, Hao, et al.
Publicado: (2019)

Diversity and Regulation of S-Adenosylmethionine Dependent Methyltransferases in the Anhydrobiotic Midge
por: Deviatiiarov, Ruslan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_orgrk27dnbti8esqg09d10vpe3