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Multimodal Registration for Image-Guided EBUS Bronchoscopy
The state-of-the-art procedure for examining the lymph nodes in a lung cancer patient involves using an endobronchial ultrasound (EBUS) bronchoscope. The EBUS bronchoscope integrates two modalities into one device: (1) videobronchoscopy, which gives video images of the airway walls; and (2) convex-p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320860/ https://www.ncbi.nlm.nih.gov/pubmed/35877633 http://dx.doi.org/10.3390/jimaging8070189 |
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author | Zang, Xiaonan Zhao, Wennan Toth, Jennifer Bascom, Rebecca Higgins, William |
author_facet | Zang, Xiaonan Zhao, Wennan Toth, Jennifer Bascom, Rebecca Higgins, William |
author_sort | Zang, Xiaonan |
collection | PubMed |
description | The state-of-the-art procedure for examining the lymph nodes in a lung cancer patient involves using an endobronchial ultrasound (EBUS) bronchoscope. The EBUS bronchoscope integrates two modalities into one device: (1) videobronchoscopy, which gives video images of the airway walls; and (2) convex-probe EBUS, which gives 2D fan-shaped views of extraluminal structures situated outside the airways. During the procedure, the physician first employs videobronchoscopy to navigate the device through the airways. Next, upon reaching a given node’s approximate vicinity, the physician probes the airway walls using EBUS to localize the node. Due to the fact that lymph nodes lie beyond the airways, EBUS is essential for confirming a node’s location. Unfortunately, it is well-documented that EBUS is difficult to use. In addition, while new image-guided bronchoscopy systems provide effective guidance for videobronchoscopic navigation, they offer no assistance for guiding EBUS localization. We propose a method for registering a patient’s chest CT scan to live surgical EBUS views, thereby facilitating accurate image-guided EBUS bronchoscopy. The method entails an optimization process that registers CT-based virtual EBUS views to live EBUS probe views. Results using lung cancer patient data show that the method correctly registered 28/28 (100%) lymph nodes scanned by EBUS, with a mean registration time of 3.4 s. In addition, the mean position and direction errors of registered sites were 2.2 mm and 11.8 [Formula: see text] , respectively. In addition, sensitivity studies show the method’s robustness to parameter variations. Lastly, we demonstrate the method’s use in an image-guided system designed for guiding both phases of EBUS bronchoscopy. |
format | Online Article Text |
id | pubmed-9320860 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-93208602022-07-27 Multimodal Registration for Image-Guided EBUS Bronchoscopy Zang, Xiaonan Zhao, Wennan Toth, Jennifer Bascom, Rebecca Higgins, William J Imaging Article The state-of-the-art procedure for examining the lymph nodes in a lung cancer patient involves using an endobronchial ultrasound (EBUS) bronchoscope. The EBUS bronchoscope integrates two modalities into one device: (1) videobronchoscopy, which gives video images of the airway walls; and (2) convex-probe EBUS, which gives 2D fan-shaped views of extraluminal structures situated outside the airways. During the procedure, the physician first employs videobronchoscopy to navigate the device through the airways. Next, upon reaching a given node’s approximate vicinity, the physician probes the airway walls using EBUS to localize the node. Due to the fact that lymph nodes lie beyond the airways, EBUS is essential for confirming a node’s location. Unfortunately, it is well-documented that EBUS is difficult to use. In addition, while new image-guided bronchoscopy systems provide effective guidance for videobronchoscopic navigation, they offer no assistance for guiding EBUS localization. We propose a method for registering a patient’s chest CT scan to live surgical EBUS views, thereby facilitating accurate image-guided EBUS bronchoscopy. The method entails an optimization process that registers CT-based virtual EBUS views to live EBUS probe views. Results using lung cancer patient data show that the method correctly registered 28/28 (100%) lymph nodes scanned by EBUS, with a mean registration time of 3.4 s. In addition, the mean position and direction errors of registered sites were 2.2 mm and 11.8 [Formula: see text] , respectively. In addition, sensitivity studies show the method’s robustness to parameter variations. Lastly, we demonstrate the method’s use in an image-guided system designed for guiding both phases of EBUS bronchoscopy. MDPI 2022-07-08 /pmc/articles/PMC9320860/ /pubmed/35877633 http://dx.doi.org/10.3390/jimaging8070189 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zang, Xiaonan Zhao, Wennan Toth, Jennifer Bascom, Rebecca Higgins, William Multimodal Registration for Image-Guided EBUS Bronchoscopy |
title | Multimodal Registration for Image-Guided EBUS Bronchoscopy |
title_full | Multimodal Registration for Image-Guided EBUS Bronchoscopy |
title_fullStr | Multimodal Registration for Image-Guided EBUS Bronchoscopy |
title_full_unstemmed | Multimodal Registration for Image-Guided EBUS Bronchoscopy |
title_short | Multimodal Registration for Image-Guided EBUS Bronchoscopy |
title_sort | multimodal registration for image-guided ebus bronchoscopy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320860/ https://www.ncbi.nlm.nih.gov/pubmed/35877633 http://dx.doi.org/10.3390/jimaging8070189 |
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