Daily Intraperitoneal Administration of Rosiglitazone Does Not Improve Lung Function or Alveolarization in Preterm Rabbits Exposed to Hyperoxia

Thiazolidinediones (TZDs) are potent PPARγ agonists that have been shown to attenuate alveolar simplification after prolonged hyperoxia in term rodent models of bronchopulmonary dysplasia. However, the pulmonary outcomes of postnatal TZDs have not been investigated in preterm animal models. Here, we...

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Detalles Bibliográficos
Autores principales: Aquila, Giorgio, Regin, Yannick, Murgia, Xabier, Salomone, Fabrizio, Casiraghi, Costanza, Catozzi, Chiara, Scalera, Enrica, Storti, Matteo, Stretti, Francesca, Aquino, Giancarlo, Cavatorta, Giorgia, Volta, Roberta, Di Pasquale, Carmelina, Amato, Caterina, Bignami, Fabio, Amidani, Davide, Pioselli, Barbara, Sgarbi, Elisa, Ronchi, Paolo, Mazzola, Giuseppe, Valenzuela, Ignacio, Toelen, Jaan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320886/
https://www.ncbi.nlm.nih.gov/pubmed/35890402
http://dx.doi.org/10.3390/pharmaceutics14071507

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