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Self-Repairing Herpesvirus Saimiri Deletion Variants

Herpesvirus saimiri (HVS) is discussed as a possible vector in gene therapy. In order to create a self-repairing HVS vector, the F plasmid vector moiety of the bacterial artificial chromosome (BAC) was transposed via Red recombination into the virus genes ORF22 or ORF29b, both important for virus re...

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Detalles Bibliográficos
Autores principales: Heyn, Ines, Bremer, Linda, Zingler, Philipp, Fickenscher, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320899/
https://www.ncbi.nlm.nih.gov/pubmed/35891505
http://dx.doi.org/10.3390/v14071525

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