Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS

OBJECTIVE: Intrathecal Immunoglobulin M synthesis (IgM(Intrathecal Fraction (IF)) (+)) and spinal MRI lesions are both strong independent predictors of higher disease activity and severity in multiple sclerosis (MS). We investigated whether IgM(IF) (+) is associated with spinal cord manifestation an...

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Detalles Bibliográficos
Autores principales: Oechtering, Johanna, Lincke, Therese, Schaedelin, Sabine, Décard, Bernhard F., Maceski, Aleksandra, Orleth, Annette, Meier, Stephanie, Willemse, Eline, Buchmann, Arabella, Khalil, Michael, Derfuss, Tobias, Benkert, Pascal, Heijnen, Ingmar, Regeniter, Axel, Müller, Stefanie, Achtnichts, Lutz, Lalive, Patrice, Salmen, Anke, Pot, Caroline, Gobbi, Claudio, Kappos, Ludwig, Granziera, Cristina, Leppert, David, Schlaeger, Regina, Lieb, Johanna M., Kuhle, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320956/
https://www.ncbi.nlm.nih.gov/pubmed/35293622
http://dx.doi.org/10.1002/ana.26348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9320956/
https://www.ncbi.nlm.nih.gov/pubmed/35293622
http://dx.doi.org/10.1002/ana.26348

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